Recombinant Full Length Human MYL3 Protein, C-Flag-tagged

• Cat.No.: MYL3-629HFL
• Product Overview: Recombinant Full Length Human MYL3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 21.8 kDa
• AA Sequence: MAPKKPEPKKDDAKAAPKAAPAPAP PPEPERPKEVEFDASKIKIEFTPEQ IEEFKEAFMLFDRTPKCEMK ITYGQCGDVLRALGQNPTQAEVLRV LGKPRQEELNTKMMDFETFLPMLQH ISKNKDTGTYEDFVEGLRVF
  DKEGNGTVMGAELRHVLATLGERLT EDEVEKLMAGQEDSNGCINYEAFVK HIMSSTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Gene Information

• Gene Name: MYL3 myosin light chain 3 [ Homo sapiens (human) ]
• Official Symbol: MYL3
• Synonyms: CMH8; VLC1; VLCl; MLC1V; MLC1SB; MLC-lV/sb
• Gene ID: 4634
• mRNA Refseq: NM_000258.3
• Protein Refseq: NP_000249.1
• MIM: 160790
• UniProt ID: P08590