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MYLK3

  • Official Full Name

    myosin light chain kinase 3

  • Synonyms

    MYLK3; myosin light chain kinase 3; putative myosin light chain kinase 3; caMLCK; MLC kinase; MLCK; cardiac-MyBP-C associated Ca/CaM kinase; cardiac-MyBP-C-associated Ca/CaM kinase; MLCK2; MGC126319; MGC126320;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Sf21
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MYLK3-151H Active Recombinant Human MYLK3(1425-1771) Protein, N-His-tagged Sf21 His 1425-1771 aa
Human MYLK3-8033H Recombinant Human MYLK3 protein, His & T7-tagged E.coli His/T7 Glu555~Ser786 (Accession # Q32MK0)
Human MYLK3-366H Recombinant Human Myosin Light Chain Kinase 3, GST-tagged, Active Sf9 Insect Cell GST
Human MYLK3-4015HCL Recombinant Human MYLK3 293 Cell Lysate HEK293 N/A
Human MYLK3-5382H Recombinant Human MYLK3 Protein, GST-tagged Wheat Germ GST
Mouse MYLK3-10323M Recombinant Mouse MYLK3 Protein Mammalian Cell His
Mouse Mylk3-8034M Recombinant Mouse Mylk3 protein, His-tagged E.coli His Gly488~Pro750 (Accession # Q3UIZ8)
Mouse MYLK3-5850M Recombinant Mouse MYLK3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MYLK3-5850M-B Recombinant Mouse MYLK3 Protein Pre-coupled Magnetic Beads HEK293
Rat MYLK3-3859R Recombinant Rat MYLK3 Protein Mammalian Cell His
Rat MYLK3-3518R Recombinant Rat MYLK3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MYLK3-3518R-B Recombinant Rat MYLK3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MYLK3-6011Z Recombinant Zebrafish MYLK3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MYLK3 Related Articles

MYLK3 involved in several pathways and played different roles in them. We selected most pathways MYLK3 participated on our site, such as Calcium signaling pathway, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYLK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayATP2A1;RYR1;PPP3CA;PRKCBB;DRD5;RYR1B;PLCE1;PPP3R2;PLCD4
cGMP-PKG signaling pathwayIRS1;SLC8A1;ITPR1;MEF2C;PPP1CC;NPPB;GUCY1B3;ATP1B2;LOC100328615
Vascular smooth muscle contractionPLA2G4F;PPP1CB;NPR1A;NPR1;CALM4;PPP1R14AA;MYL6B;PRKCB;ADCY1A
Focal adhesionCCND2A;DOCK1;Reln;AKT1;Pdgfa&Pdgfb;SPP1;ROCK2A;PXN;RAP1B
Platelet activationARHGEF12;ITGB3;FYN;ITGB1;FCER1G;MAPK3;PLCG2;GNAS;P2RY12
Regulation of actin cytoskeletonVCLA;VCL;MOS;ARHGEF7;WASLA;FN1A;HRAS;EZRB;ACTN3
Oxytocin signaling pathwayMAP2K5;CACNB1;MAPK1;FOS;NFATC3;PPP1R12A;MYLK;PPP1CC;MAP2K1
Gastric acid secretionATP1A1;CCKBR;Adcy4;SSTR2;GNAI2;PRKCA;GNAI3;PLCB2;CALM3

MYLK3 has several biochemical functions, for example, ATP binding, calmodulin-dependent protein kinase activity, myosin light chain kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MYLK3 itself. We selected most functions MYLK3 had, and list some proteins which have the same functions with MYLK3. You can find most of the proteins on our site.

Function Related Protein
ATP bindingNLRP10;MLKL;TNIK;PINK1;PKN1;MAP4K1;BMP2K;BMPR2B;LARS
calmodulin-dependent protein kinase activityDAPK1;PNCK;DCX;MKNK2A;MYLK3;CAMK2A;CAMKK2;MAPKAPK2;CAMK2B
myosin light chain kinase activityMYLK2;MYLK3;MYLK

MYLK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYLK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYLK3.

HSP90AB1; ALB

Wang, HG; Dong, JN; et al. Anti-mouse CD52 monoclonal antibody ameliorates intestinal epithelial barrier function in interleukin-10 knockout mice with spontaneous chronic colitis. IMMUNOLOGY 144:254-262(2015).
Ayoglu, B; Chaouch, A; et al. Affinity proteomics within rare diseases: a BIO-NMD study for blood biomarkers of muscular dystrophies. EMBO MOLECULAR MEDICINE 6:918-936(2014).
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