ndufs5
Share
  • Official Full Name
  • NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
  • Background
  • This gene is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 1, 4 and 17.
  • Synonyms
  • NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase); NADH dehydrogenase (ubiquinone) Fe S protein 5 (15kD) (NADH coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 5; CI 15k; complex I 51kDa subunit; NADH dehydrogenase [ubiquinone] iron sulfur protein 5; CI-15 kDa; Complex I-15 kDa; NADH-ubiquinone oxidoreductase 15 kDa subunit; NADH:ubiquinone oxidoreductase 15 kDa IP subunit; CI15K; CI-15k
Cat.#:NDUFS5-1241HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NDUFS5, His-tagged
+Inquiry
Cat.#:NDUFS5-5060HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NDUFS5, His-tagged
+Inquiry
Cat.#:NDUFS5-10545MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NDUFS5 Protein
+Inquiry
Cat.#:NDUFS5-739CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus NDUFS5 Protein, His-tagged
+Inquiry
Cat.#:NDUFS5-2808ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NDUFS5
+Inquiry
Cat.#:NDUFS5-3894HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NDUFS5 293 Cell Lysate
+Inquiry

Involved Pathway

NDUFS5 involved in several pathways and played different roles in them. We selected most pathways NDUFS5 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Oxidative phosphorylation
NDUFS7; ATP6V0A1B; ATP5H; NDUFB5; ATP6V1E2; UQCR10; NDUFS8; ATP5E; PPA1; COX7B2
Metabolic pathways
PIP5K1BA; ACSL4; C1GALT1C1; GCNT1; INPP4B; P4HA1A; PPAT; P4HA1; UAP1L1; PCYT1AB
Non-alcoholic fatty liver disease (NAFLD)
NDUFA1; EIF2AK3; INS; ERN1; TRAF2; COX7B2; ADIPOQ; PPARA; NDUFB11; MAPK9
Alzheimers disease
NDUFS6; NDUFA8; COX6C; UQCRFS1; MAPK3; RYR3; NDUFA5; COX5B; NDUFS1; NCSTN
Parkinsons disease
TH; PINK1; NDUFS3; NDUFC2-KCTD14; ATP5D; SLC25A5; NDUFB4; GNAI3; SLC25A4; NDUFA9
Huntingtons disease
UQCR11; UQCRQ; NDUFV1; NDUFS3; NDUFA11; POLR2K; NDUFA7; SLC25A31; DNAI2; DNAH6

Protein Function

NDUFS5 has several biochemical functions, for example, NADH dehydrogenase (ubiquinone) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFS5 itself. We selected most functions NDUFS5 had, and list some proteins which have the same functions with NDUFS5. You can find most of the proteins on our site.
Function
Related Protein
Function NADH dehydrogenase (ubiquinone) activity
Related Protein NDUFB7; NDUFB3; NDUFB5; NDUFA8; NDUFV2; NDUFA5; NDUFS7; NDUFA7; NDUFB8; NDUFS6

Interacting Protein

NDUFS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFS5.
NDUFA2; NDUFA6; NDUFAF1; NR4A2; NDUFS8; COX7A2L; NDUFS4; NDUFB5; NDUFS7; NDUFS2; NDUFS6; NDUFS3; NDUFB6; NDUFB4; NDUFB8; NDUFA7