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Official Full Name nebulette
Background This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.
Synonyms NEBL; nebulette; LIM-nebulette; actin-binding Z-disk protein; LASP2; LNEBL; FLJ53769; MGC119746; MGC119747
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NEBL-1485H Recombinant Human NEBL Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Nebl-4351M Recombinant Mouse Nebl Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human NEBL-1246H Recombinant Human NEBL, GST-tagged E.coli GST
    Human NEBL-590H Recombinant Human NEBL Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse NEBL-10552M Recombinant Mouse NEBL Protein Mammalian Cell His
    Chicken NEBL-6058C Recombinant Chicken NEBL Mammalian Cell His
    Zebrafish NEBL-2224Z Recombinant Zebrafish NEBL Mammalian Cell His

    NEBL involved in several pathways and played different roles in them. We selected most pathways NEBL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NEBL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    NEBL has several biochemical functions, for example, actin filament binding, cytoskeletal protein binding, filamin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEBL itself. We selected most functions NEBL had, and list some proteins which have the same functions with NEBL. You can find most of the proteins on our site.

    Function Related Protein
    actin filament binding AIF1; MYO6; MTSS1; SYNE2; BLOC1S6; SHROOM3; PPP1R9A; EZR; VPS16; ERMN
    cytoskeletal protein binding ALDOB; PTPN3; FRMD3; ALDOC; NCKIPSD; EPB41L3A; RPH3AL; PDLIM3; NF2A; ABI1
    filamin binding PDLIM2; FAM101A; FBLIM1; FAM101B; ZNF664-FAM101A; MICALL2; TMEM67; NEBL; HSPB7
    protein binding DCDC2; DNAI2; C6orf211; RNASEL; PYROXD1; ATG16L1; KCNJ3; TUBB2A; USP46; ALKBH8
    structural constituent of muscle TPM4; TTN; MYLPF; MYH11; ANKRD2; MYBPC3; MYL2; MYBPH; MYL5; TPM2
    tropomyosin binding NEBL; LMOD3; TNNT3; S100A6; TMOD3; LMOD1; LMOD2A; TNNT2A; PYCARD; TMOD1

    NEBL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEBL here. Most of them are supplied by our site. Hope this information will be useful for your research of NEBL.

    b2r8y4_human; HOMER3; TRIM27; GOLGA2; TRAF2; TRAF1; FLJ13057

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