NKAP
-
Official Full Name
NFKB activating protein
-
Overview
This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. -
Synonyms
NKAP; NFKB activating protein; NF-kappa-B-activating protein; FLJ22626; NF kappaB activating protein; NF-kappaB activating protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- NKAP Related Signal Pathway
NKAP involved in several pathways and played different roles in them. We selected most pathways NKAP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NKAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
NKAP has several biochemical functions, for example, chromatin DNA binding, chromatin binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKAP itself. We selected most functions NKAP had, and list some proteins which have the same functions with NKAP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chromatin DNA binding | RXRA;THRA;SLAMF7;HIST1H1C;FOXC2;MYOD1;H1F0;H2AFY2;HIST1H1D |
| chromatin binding | TRPS1;HESX1;L3MBTL1;EGFR;SKI;TOX3;MTA1;JMJD5;CBFA2T3 |
| poly(A) RNA binding | Api5;COX4I2;NOC3L;TRUB2;MRPL45;SART3;DDX52;TRMT2A;CPEB3 |
| protein binding | EPHB1;VAT1L;FAM110A;CSRP3;MSI2;GDPD5;DNAIC2;VASP;IL10RB |
NKAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKAP here. Most of them are supplied by our site. Hope this information will be useful for your research of NKAP.
PRPF3; PRPF40A; U2AF1; DHX8; DDX41; RBMX2; tax; SRPK1; RNPS1; Ddx41; DHX15; BUB3; NOS1AP
- Q&As
- Reviews
Ask a Question for All NKAP Products
Required fields are marked with *
My Review for All NKAP Products
Required fields are marked with *
