nmt2
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  • Official Full Name
  • N-myristoyltransferase 2
  • Background
  • N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It;transfers myristic acid from myristoyl coenzyme A to the amino group of a proteins N-terminal glycine residue.;Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or;subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with;human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases.
  • Synonyms
  • NMT2; N-myristoyltransferase 2; glycylpeptide N-tetradecanoyltransferase 2; NMT 2; type II N-myristoyltransferase; peptide N-myristoyltransferase 2; myristoyl-CoA:protein N-myristoyltransferase 2
Cat.#:NMT2-112HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human NMT2 protein, GST-tagged
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Cat.#:NMT2-27990THTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NMT2, T7 -tagged
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Cat.#:NMT2-3434HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NMT2 protein, His-tagged
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Cat.#:NMT2-826HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human N-myristoyltransferase 2, T7-tagged
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Cat.#:NMT2-10755MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NMT2 Protein
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Cat.#:NMT2-7877ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NMT2
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Cat.#:NMT2-3782HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NMT2 293 Cell Lysate
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Involved Pathway

NMT2 involved in several pathways and played different roles in them. We selected most pathways NMT2 participated on our site, such as Assembly Of The HIV Virion, Disease, HIV Infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with NMT2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Assembly Of The HIV Virion
NMT2; gag; PPIA; VPS37A
Disease
PRELP; TIRAP; TLR6; CCDC167; CHMP4C; AP1M2; LRRFIP1; FGFR1OP2; TLR10; EPM2A
HIV Infection
RCC1; NMT1; NPM1; VPS37A; PPIAL4A; AP1B1; AP1M2; DOCK2; TCEB3; CDK9
HIV Life Cycle
CDK9; CHMP4B; RCC1; SSRP1; VPS37A; TCEB3; NMT1; NMT2; PSTPIP2; ELL
Inactivation, recovery and regulation of the phototransduction cascade
METAP1; RHOL; NMT1A; CNGA1; GRK7; GNB5A; METAP2; RGS9BP; NMT1; METAP2A
Infectious disease
CCDC167; PACS1; TAF1L; VPS37A; CHMP4B; CHMP4C; ANTXR2; ANTXR1; EEF2; SYT2
Late Phase of HIV Life Cycle
NMT2; PDCD6IP; TAF1L; RCC1
Membrane binding and targetting of GAG proteins
NMT2

Protein Function

NMT2 has several biochemical functions, for example, glycylpeptide N-tetradecanoyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NMT2 itself. We selected most functions NMT2 had, and list some proteins which have the same functions with NMT2. You can find most of the proteins on our site.
Function
Related Protein
Function glycylpeptide N-tetradecanoyltransferase activity
Related Protein NMT2; NMT1B; NMT1; NMT1A

Interacting Protein

NMT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NMT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NMT2.
TP53; BCL2; CASP3; TK1; ANXA4; ANXA7; CSNK2B; PRKCZ; SMN1; TMED9

NMT2 Related Articles

Nasr, R; Johns, C; et al. Collapsing glomerulopathy in collagen vascular-like disease. LUPUS 23:75-80(2014).
Yu, C; Xu, L; et al. PRBC-derived plasma induces non-muscle myosin type IIA-mediated neutrophil migration and morphologic change. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 35:71-79(2013).