|Official Full Name||nuclear receptor subfamily 1, group D, member 2|
|Background||This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.|
|Synonyms||NR1D2; nuclear receptor subfamily 1, group D, member 2; nuclear receptor subfamily 1 group D member 2; BD73; EAR 1r; Hs.37288; HZF2; RVR; EAR-1R; NR1D2_HUMAN; Orphan nuclear hormone receptor BD73; Rev erb beta; Rev-erb-beta; REVB; REVERBB; V-erbA-related protein 1-related; OTTHUMP00000208397; rev-erba-alpha-related receptor; nuclear receptor Rev-ErbA beta variant 1; nuclear receptor Rev-ErbA beta var|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
NR1D2 involved in several pathways and played different roles in them. We selected most pathways NR1D2 participated on our site, such as Diurnally regulated genes with circadian orthologs, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR1D2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Diurnally regulated genes with circadian orthologs||GFRA1; QK; SF3A3; DAZAP2; MYF6; PURA; NCKAP1; CEBPB; CRY2; EIF4G2|
|Gene Expression||LBH; PTBP1B; ZNF167; SKIB; ZNF192; MTERF; ZNF577; ZNF559; WHSC2; MED25|
|Generic Transcription Pathway||ZNF544; ZNF689; COX6A1; ZNF684; ZNF498; ZNF697; GLS2B; MED16; ZFP37; ZNF445|
|Nuclear Receptor transcription pathway||NR5A1A; NR1D2; NR1D2B; NR1I3; RARG; NR0B2A; ESRRGA; ESRRG; ESR2B; VDRB|
|Nuclear Receptors||ROR1; RORAA; NR2F6; NR1I3; NR0B1; RARGA; NR4A2A; NR1D2B; NR1H3; NR2C2|
NR1D2 has several biochemical functions, for example, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding, core promoter sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NR1D2 itself. We selected most functions NR1D2 had, and list some proteins which have the same functions with NR1D2. You can find most of the proteins on our site.
|RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding||NR2F1B; NR5A1; NR1D2; ESRRA; PPARG; NR1I2; PPARA; NR4A2; PTGER3; NR2F1A|
|core promoter sequence-specific DNA binding||PPARG; ZFHX3; NFYA; ZFP932; NRF1; SOHLH1; ESR2; SP1; ATF4; C1orf51|
|protein binding||DYNLT3; TSHZ3; CTGF; PPP2R5A; IGFLR1; KLK4; CREB3L1; QARS; CFI; SCGB2A2|
|steroid hormone receptor activity||GPR30; RARG; VDRA; RARAA; NR2E3; NR0B2; RORCB; NR2F6A; THRA; PPARDB|
|zinc ion binding||FBXO30; ADAMTS8; HE1B; AKT1S1; ADAT2; GTF2H2; MMEL1; SF3A3; TLL2; DPF3|
NR1D2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR1D2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR1D2.
Clock; PRMT6; BHLHE40; CSNK2A2; RORC; Cry1; Csnk1e