|Official Full Name||nuclear receptor subfamily 6, group A, member 1|
|Background||This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2013]|
|Synonyms||NR6A1; nuclear receptor subfamily 6, group A, member 1; RTR; GCNF; NR61; hRTR; CT150; GCNF1; hGCNF; nuclear receptor subfamily 6 group A member 1; germ cell nuclear factor variant 1; retinoid receptor-related testis-specific receptor; retinoic acid receptor-related testis-associated receptor;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
NR6A1 involved in several pathways and played different roles in them. We selected most pathways NR6A1 participated on our site, such as Developmental Biology, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR6A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Developmental Biology||DPYSL4; PEBP1; EPHA10; RGMB; RHOC; MED25; ACTR3; ADAM23; CLTB; FRS2B|
|Gene Expression||SNAPC3; CHST13; HUG; SNRNP35; ZNF557; TUBB3; LAMTOR1; SSRP1; CBX3A; POLR3F|
|Generic Transcription Pathway||ZNF556; RXRBB; CDK9; ZKSCAN1; MED20; ZNF468; SKI; ZNF19; ZNF354B; ZNF668|
|Nuclear Receptor transcription pathway||RARAA; NR5A1A; NR1I2; ESRRG; NR1D2A; NR2C2; NR2F1; ESR2A; RARAB; NR1D2B|
|POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation||FOXD3; TDGF1; NR6A1|
|Transcriptional regulation of pluripotent stem cells||SALL4; NR6A1; POU5F3; PRDM14; NR5A1; LIN28A; HIF3A; TDGF1; FOXD3|
NR6A1 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NR6A1 itself. We selected most functions NR6A1 had, and list some proteins which have the same functions with NR6A1. You can find most of the proteins on our site.
|DNA binding||HDGF; NR4A1; TNP1; HIST1H1T; NEUROG1; ZFP131; ZNF781; HOXC9A; SPI1B; ZNF189|
|RNA polymerase II core promoter proximal region sequence-specific DNA binding||FOSL1; ISL1; NKX2-8; ZNF680; MED1; TCF4; CEBPB; MESP1; MYOD1; FOXK2|
|RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding||NR2F6; NR2E3; NR4A2; PTGER3; PPARDB; RORCA; NR5A1A; NR2F2; AHR; NR5A2|
|protein homodimerization activity||CUL3; MFF; UGT1A9; GGCT; LRP6; MZF1; ADRB3; MAP3K10; CADM1B; MIXL1|
|sequence-specific DNA binding||NKX2-8; ZFP423; GATAD1; PBX1A; NKX2.5; NFE2L2B; MNX1; FOXS1; FOXI3B; NKX2-3|
|steroid hormone receptor activity||PGR; RXRG; NR1D2B; ESR1; NR4A2; NR4A2B; PGRMC2; NR1H5; NR1D4B; NR2F6|
|transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding||GATA2; ATOH1; POU3F2; ONECUT3; SMAD4; POU2F2; NFATC2; MEF2B; EHF; MIXL1|
|zinc ion binding||TRAF4; ZCCHC11; ZDHHC17; ZNF184; BTR06; TRPS1; MT3; MICALL2; PHRF1; TRIM35-28|
NR6A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR6A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR6A1.