NR6A1 Protein, nuclear receptor subfamily 6, group A, member 1


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Official Full Name nuclear receptor subfamily 6, group A, member 1
Background This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2013]
Synonyms NR6A1; nuclear receptor subfamily 6, group A, member 1; RTR; GCNF; NR61; hRTR; CT150; GCNF1; hGCNF; nuclear receptor subfamily 6 group A member 1; germ cell nuclear factor variant 1; retinoid receptor-related testis-specific receptor; retinoic acid receptor-related testis-associated receptor;
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NR6A1-26466TH Recombinant Human NR6A1 Wheat Germ N/A
    Human NR6A1-3704HCL Recombinant Human NR6A1 293 Cell Lysate HEK293 N/A
    Human NR6A1-6102H Recombinant Human NR6A1 Protein, GST-tagged Wheat Germ GST
    Human NR6A1-7840H Recombinant Human NR6A1 protein, His & T7-tagged E.coli His/T7
    Mouse NR6A1-10876M Recombinant Mouse NR6A1 Protein Mammalian Cell His

    NR6A1 involved in several pathways and played different roles in them. We selected most pathways NR6A1 participated on our site, such as Developmental Biology, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR6A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Developmental Biology DPYSL4; PEBP1; EPHA10; RGMB; RHOC; MED25; ACTR3; ADAM23; CLTB; FRS2B
    Gene Expression SNAPC3; CHST13; HUG; SNRNP35; ZNF557; TUBB3; LAMTOR1; SSRP1; CBX3A; POLR3F
    Generic Transcription Pathway ZNF556; RXRBB; CDK9; ZKSCAN1; MED20; ZNF468; SKI; ZNF19; ZNF354B; ZNF668
    Nuclear Receptor transcription pathway RARAA; NR5A1A; NR1I2; ESRRG; NR1D2A; NR2C2; NR2F1; ESR2A; RARAB; NR1D2B
    POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation FOXD3; TDGF1; NR6A1
    Transcriptional regulation of pluripotent stem cells SALL4; NR6A1; POU5F3; PRDM14; NR5A1; LIN28A; HIF3A; TDGF1; FOXD3

    NR6A1 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NR6A1 itself. We selected most functions NR6A1 had, and list some proteins which have the same functions with NR6A1. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding HDGF; NR4A1; TNP1; HIST1H1T; NEUROG1; ZFP131; ZNF781; HOXC9A; SPI1B; ZNF189
    RNA polymerase II core promoter proximal region sequence-specific DNA binding FOSL1; ISL1; NKX2-8; ZNF680; MED1; TCF4; CEBPB; MESP1; MYOD1; FOXK2
    RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding NR2F6; NR2E3; NR4A2; PTGER3; PPARDB; RORCA; NR5A1A; NR2F2; AHR; NR5A2
    protein homodimerization activity CUL3; MFF; UGT1A9; GGCT; LRP6; MZF1; ADRB3; MAP3K10; CADM1B; MIXL1
    sequence-specific DNA binding NKX2-8; ZFP423; GATAD1; PBX1A; NKX2.5; NFE2L2B; MNX1; FOXS1; FOXI3B; NKX2-3
    steroid hormone receptor activity PGR; RXRG; NR1D2B; ESR1; NR4A2; NR4A2B; PGRMC2; NR1H5; NR1D4B; NR2F6
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GATA2; ATOH1; POU3F2; ONECUT3; SMAD4; POU2F2; NFATC2; MEF2B; EHF; MIXL1
    zinc ion binding TRAF4; ZCCHC11; ZDHHC17; ZNF184; BTR06; TRPS1; MT3; MICALL2; PHRF1; TRIM35-28

    NR6A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR6A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR6A1.


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