nudt9
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  • Official Full Name
  • nudix (nucleoside diphosphate linked moiety X)-type motif 9
  • Background
  • The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • NUDT9; nudix (nucleoside diphosphate linked moiety X)-type motif 9; ADP-ribose pyrophosphatase, mitochondrial; MGC3037; mitochondrial; Adenosine diphosphoribose pyrophosphatase; ADP ribose diphosphatase; ADP ribose phosphohydrolase; ADP ribose pyrophosphatase, mitochondrial precursor; ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ADP-ribose pyrophosphatase; ADPR PPase; ADPR-PPase; EC 3.6.1.13; Nucleoside diphosphate linked moiety X motif 9; Nucleoside diphosphate-linked moiety X motif 9; Nudix motif 9; NUDT9_HUMAN; ADP-ribose pyrosphosphatase NUDT9; nucleoside diphosphate linked moiety X-type motif 9; NUDT10
Cat.#:NUDT9-994HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT9, His-tagged
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Cat.#:NUDT9-1408HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT9, His-tagged
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Cat.#:NUDT9-10980MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NUDT9 Protein
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Cat.#:NUDT9-4122RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat NUDT9 Protein
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Cat.#:NUDT9-3132RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NUDT9 Protein, His-tagged
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Cat.#:NUDT9-12532ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NUDT9
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Cat.#:NUDT9-3639HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human NUDT9 293 Cell Lysate
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Cat.#:NUDT9-3640HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human NUDT9 293 Cell Lysate
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Involved Pathway

NUDT9 involved in several pathways and played different roles in them. We selected most pathways NUDT9 participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Purine metabolism
PAICS; GDA; PKMB; POLR1D; GMPS; ADA; ADK; ENTPD3; ADKB; ADKA

Protein Function

NUDT9 has several biochemical functions, for example, ADP-ribose diphosphatase activity, ADP-sugar diphosphatase activity, adenosine-diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT9 itself. We selected most functions NUDT9 had, and list some proteins which have the same functions with NUDT9. You can find most of the proteins on our site.
Function
Related Protein
Function ADP-ribose diphosphatase activity
Related Protein ADPRM; NUDT14; TRPM2; NUDT5; NUDT9
Function ADP-sugar diphosphatase activity
Related Protein NUDT5; NUDT9
Function adenosine-diphosphatase activity
Related Protein ENTPD2; NUDT9; SLC25A42

Interacting Protein

NUDT9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT9 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT9.
MDM2; EPHA2