|Official Full Name||2-5-oligoadenylate synthetase 3, 100kDa|
|Background||This gene encodes an enzyme included in the 2, 5 oligoadenylate synthase family.This enzyme is induced by interferons and catalyzes the 2, 5 oligomers of adenosine in order to bind and activate RNase L.This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.|
|Synonyms||OAS3; 2-5-oligoadenylate synthetase 3, 100kDa; 2 5 oligoadenylate synthetase 3 (100 kD); 2-5-oligoadenylate synthase 3; p100OAS; p100 OAS; 2-5A synthase 3; 2-5A synthetase 3; (2-5)oligo(A) synthase 3; (2-5)oligo(A) synthetase 3; 2-5oligoadenylate syntheta|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
OAS3 involved in several pathways and played different roles in them. We selected most pathways OAS3 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with OAS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Hepatitis C||CLDN4; IFNA8; CLDN23; CLDN15; CLDN7; TRAF2; CLDN9; IL-8; PPP2R2A; MAPK11|
|Measles||HSPA2; IL1B; IFNA7; TACR1; IFNG; TLR9; IRF3; CD209A; cgr2b; RAB9B|
|Influenza A||TLR7; PIK3CG; SLC25A6; RELA; PIK3R2; IL12B; PIK3R1; TLR3; CYCS; MAPK11|
|Herpes simplex infection||SRPK1B; IFNB1; RELA; FAS; EIF2AK1; MAPK8A; MYD88; PPP1CAA; EIF2AK4; CSNK2A2|
OAS3 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by OAS3 itself. We selected most functions OAS3 had, and list some proteins which have the same functions with OAS3. You can find most of the proteins on our site.
|2-5-oligoadenylate synthetase activity||OAS3; OAS2; OAS1; OASL2; OAS1A|
|ATP binding||DNAJA4; ERBB3B; ATP1A2A; UCK2; EIF2B2; DDX5; SPO11; MAT2AL; SHPRH; DCLK1|
|double-stranded RNA binding||MBNL1; TUBB4B; TUBA1B; DROSHA; OAS1; OAS1A; DHX15; TLR8; HSPD1; IFIH1|
|metal ion binding||KLF7A; ZNF789; MYO9B; LMAN1; ZFP161; ARSH; CYP2K18; PCK2; B3GNT1; HMGCLL1|
|protein binding||MATK; PODXL2; AJUBA; OTUB2; PRL; KEL; GAPDHS; TOMM7; SNAI2; CYSLTR2|
OAS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OAS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of OAS3.
EIF6; IFRD2; DHX30; MAVS; FTSJ3; PPM1G; CCDC22; TOP1; HIST1H1C; PABPC4; Eea1; ZNF622; GNL3; GTPBP4; LYAR