oprk1
Share
  • Official Full Name
  • opioid receptor, kappa 1
  • Background
  • The κ-opioid receptor (KOR) is a protein that in humans is encoded by the OPRK1 gene. The κ-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering the perception of pain, consciousness, motor control, and mood.
  • Synonyms
  • OPRK1; K-OR-1; Kappa type opioid receptor; Kappa-type opioid receptor; KOR 1; KOR; KOR-1; Opiate receptor kappa 1; OPRK 1; OPRK; OPRK_HUMAN; Oprk2; R21; opioid receptor, kappa 1; OTTHUMP00000226313; Opioid Receptor, kappa; OTTHUMP00000226316; kappa opioid receptor; Opiate receptor, kappa-1
Cat.#:OPRK1-28446THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human OPRK1
+Inquiry
Cat.#:OPRK1-12174MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse OPRK1 Protein
+Inquiry
Cat.#:OPRK1-4194RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat OPRK1 Protein
+Inquiry
Cat.#:OPRK1-9675ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish OPRK1
+Inquiry
Cat.#:Kit-1066Tag:
Source (Host):Species:
Product nameUric Acid Colorimetric/Fluorometric Assay Kit
+Inquiry
Cat.#:Kit-1453Tag:
Source (Host):Species:
Product namecAMP OPRK1 CHO-K1 GPCR Assay Kit
+Inquiry
Cat.#:Kit-1454Tag:
Source (Host):Species:
Product nameOPRK1 U2OS β-Arrestin GPCR Assay Kit
+Inquiry
Cat.#:Kit-1455Tag:
Source (Host):Species:
Product nameOPRK1 Total GPCR Internalization Assay Kit
+Inquiry
Cat.#:Kit-0897Tag:
Source (Host):Species:
Product nameTR-FRET TR alpha Coactivator Assay Kit, goat
+Inquiry
Cat.#:CSC-RG0034Tag:
Source (Host):Species:Human
Product nameHuman OPRK1-tGFP Stable Cell Line-U2OS
+Inquiry
Cat.#:CSC-RG0342Tag:
Source (Host):Species:Human
Product nameHuman OPRK1-FLAG Stable Cell Line-CHO
+Inquiry
Cat.#:CSC-RG0343Tag:
Source (Host):Species:Human
Product nameHuman OPRK1-FLAG Stable Cell Line-HEK293T
+Inquiry
Cat.#:CSC-RG0512Tag:
Source (Host):Species:Human
Product nameHuman OPRK1/Gi Stable Cell Line-CHO
+Inquiry
Cat.#:CSC-RG0710Tag:
Source (Host):Species:Human
Product nameHuman OPRK1/Galpha15 Stable Cell Line-Chem-1
+Inquiry
Cat.#:CSC-RG0867Tag:
Source (Host):Species:Human
Product nameHuman OPRK1 Stable Cell Line-CHO
+Inquiry
Cat.#:CSC-RG0868Tag:
Source (Host):Species:Human
Product nameHuman OPRK1 Stable Cell Line-CHO
+Inquiry
Cat.#:CSC-RG0869Tag:
Source (Host):Species:Human
Product nameHuman OPRK1 Stable Cell Line-HEK293-CNG
+Inquiry
Cat.#:CSC-RG0341Tag:
Source (Host):Species:Rat
Product nameRat Oprk1 Stable Cell Line-CHO dhfr-
+Inquiry

Involved Pathway

OPRK1 involved in several pathways and played different roles in them. We selected most pathways OPRK1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with OPRK1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Neuroactive ligand-receptor interaction
MCHR2; CHRM2A; HTR2C; GNRHR4; GRIA4B; CHRNA10; VIPR1B; CHRNA4; F2RL2; HTR7

Protein Function

OPRK1 has several biochemical functions, for example, dynorphin receptor activity, neuropeptide binding, opioid receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OPRK1 itself. We selected most functions OPRK1 had, and list some proteins which have the same functions with OPRK1. You can find most of the proteins on our site.
Function
Related Protein
Function dynorphin receptor activity
Related Protein OPRK1
Function neuropeptide binding
Related Protein OPRD1A; SSTR4; OPRK1; OPRD1; GPR1; OPRM1; NPY8BR; GPR149; OPRD1B; SSTR5
Function opioid receptor activity
Related Protein OGFR; NPBWR1; OPRK1; OPRD1; NPBWR2; OPRD1B; SIGMAR1; OPRD1A
Function protein binding
Related Protein RNF7; GRHL3; BMPR1AA; TMEM132D; TXLNA; POLE4; ECHS1; ITGAX; PPP1R11; ARF5

Interacting Protein

OPRK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OPRK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OPRK1.
GABARAPL1; GPRASP1; u69593; u50488; SLC9A3R1; SIAH2; GJA4; WLS; SIAH1; VAPA; AUP1; GABARAP; GABARAPL1

OPRK1 Related Articles

Faisal, M; Waseem, D; et al. A molecular prospective provides new insights into implication of PDYN and OPRK1 genes in alcohol dependence. COMPUTERS IN BIOLOGY AND MEDICINE 53:250-257(2014).
Trescot, AM; Faynboym, S; et al. A Review of the Role of Genetic Testing in Pain Medicine. PAIN PHYSICIAN 17:425-445(2014).

OPRK1 Related Gene Family

GPCRs