PARP3

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PARP3

Official Full Name poly (ADP-ribose) polymerase family, member 3
Background The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms PARP3; poly (ADP-ribose) polymerase family, member 3; ADP ribosyltransferase (NAD+; poly (ADP ribose) polymerase) like 3 , ADPRTL3; poly [ADP-ribose] polymerase 3; ADPRT3; hPARP 3; IRT1; NAD+ ADP ribosyltransferase 3; pADPRT 3; poly(ADP ribose) polymerase
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Insect Cells
    • Mammalian Cell
    • Sf21 Insect Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • HA
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PARP3-642H Recombinant Human PARP3 Protein, His-tagged Insect Cells His
    Human PARP3-2607H Recombinant Human PARP3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Parp3-4679M Recombinant Mouse Parp3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human PARP3-1533H Recombinant Human PARP3, GST-tagged E.coli GST
    Human PARP3-27634TH Recombinant Human PARP3, GST-tagged GST
    Human PARP3-304H Recombinant Human PARP3 Protein, His & GST-tagged Insect Cell His/GST
    Human PARP3-432H Recombinant Human PARP3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human PARP3-434H Recombinant Human Poly (ADP-ribose) Polymerase 3, GST-tagged Sf9 Insect Cell GST
    Human PARP3-454H Recombinant Human PARP3, HA-tagged Sf21 Insect Cell HA
    Human PARP3-525HCL Recombinant Human PARP3 cell lysate Insect Cell N/A
    Human PARP3-59H Recombinant Human PARP-3 Sf9 Insect Cell N/A
    Zebrafish PARP3-10795Z Recombinant Zebrafish PARP3 Mammalian Cell His
    Kit-1802 PARP3 Chemiluminescent Assay Kit N/A

    PARP3 involved in several pathways and played different roles in them. We selected most pathways PARP3 participated on our site, such as Base excision repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with PARP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Base excision repair LIG1; MPG; POLL; PARP2; HMGB1B; HMGB1A; APEX2; MBD4; xthA; PARP4

    PARP3 has several biochemical functions, for example, NAD+ ADP-ribosyltransferase activity, catalytic activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PARP3 itself. We selected most functions PARP3 had, and list some proteins which have the same functions with PARP3. You can find most of the proteins on our site.

    Function Related Protein
    NAD+ ADP-ribosyltransferase activity ART3; PARP6; PARP12; GIG2E; PARP9; TNKS; GIG2K; CHAT1; GIG2O; SIRT4
    catalytic activity CWF19L1; PKMB; HOGA1; ACAA1A; HSD3B6; APOBEC2B; ACSL1B; ACSL1; DPYDB; SULF2B

    PARP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PARP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PARP3.

    MTHFD2; RPA3; HIST2H2BE; HIST2H3D

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