PC
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Official Full Name
pyruvate carboxylase
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Overview
Rabbit polyclonal antibodies in Dulbecco’s phosphate buffered saline, pH 7.2, with 1 mg/mL BSA. 0.05% sodium azide. -
Synonyms
PC; pyruvate carboxylase; pyruvate carboxylase, mitochondrial; PCB; pyruvic carboxylase;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Chicken
- Human
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- PC Related Articles
PC involved in several pathways and played different roles in them. We selected most pathways PC participated on our site, such as Citrate cycle (TCA cycle), Pyruvate metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Citrate cycle (TCA cycle) | IDH1;PDHB;DLD;SDHB;ACLY;DLAT;MDH2;IDH3A;FH1 |
Pyruvate metabolism | MDH2;PKM;PKLR;MDH1AA;ACSS2L;LDHBB;GRHPRA;PDHA2;PDPR |
Metabolic pathways | PLA2G6;ACADL;NME2;MTMR3;GALNT12;SI;G6PC;FBP1B;POLR2I |
Carbon metabolism | ENO1B;ACAT2;ackA;ALDOCA;FBP2;GPIA;PGAM1;GPR19;ENO1 |
Biosynthesis of amino acids | MAT2A;PRPS1;MTR;PKM2;TKTB;ENO1A;ACO2;BCAT2;CPS1 |
PC has several biochemical functions, for example, ATP binding, DNA binding, biotin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PC itself. We selected most functions PC had, and list some proteins which have the same functions with PC. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
ATP binding | P2RX1;NMRK2;PRKCH;PRKY;FIGN;ATP2A2A;C22orf28;PRKACBA;ERN1 |
DNA binding | SOX21;HIST1H111L;TADA2B;RFX2;HOXB13A;ZNF800;RAD50;BANF2;CHST13 |
biotin binding | MCCC1;PCCA;PCXB;PCXA;PC;HLCS;AVR2 |
biotin carboxylase activity | PC;PCXB;PCXA;ACACB;ACACA;PCCA;MCCC1 |
metal ion binding | ZNF584;KLK1B4;CYB561;ZFP553;DYTN;PPM1NB;HNRNPA0L;NR1D2A;ZBTB8A |
protein binding | FBP2;ZBTB2;APEH;SUGP1;TDRKH;POLB;CCT3;F3;PLK4 |
pyruvate carboxylase activity | PCXB;PCXA;PC |
PC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PC here. Most of them are supplied by our site. Hope this information will be useful for your research of PC.
q03463-pro_0000278740; PPP2R2B; q99ib8-pro_0000045602; Ckap5; polg_hcvjf_rna; XRCC3; ERBB2; IFIT1; RAB7A; DYNLL1; Tubg1
- Q&As
- Reviews
Q&As (6)
Ask a questionThe structure of the PC protein determines its ability and stability to bind to DNA. The study of its structure can help us understand its function and mechanism of action.
Therapeutic strategies for PC protein may include inhibiting its expression, blocking its binding to DNA, or regulating its associated signal transduction pathways. These methods may have potential applications in cancer treatment.
In cancer, PC proteins may play a role by promoting processes such as DNA replication, repair, and regulation of the cell cycle, thus promoting tumor growth and spread. It could be a potential target for cancer treatment.
Drug development targeting PC proteins needs to consider their specificity, safety, pharmacokinetic properties, and potential side effects. In addition, issues such as the dosage form, route of administration and design of clinical trials need to be considered.
The proteins can interact with a variety of other proteins, including DNA repair enzymes, cell cycle regulators, and more. These interactions allow it to regulate the regulatory processes of DNA replication, repair and the cell cycle.
Recently published articles indicate that the expression level of PC protein is related to the occurrence and development of certain cancers. The highly expressed PC protein may promote tumor growth and spread and thus may be a potential therapeutic target.
Customer Reviews (3)
Write a reviewWith the use of PC, the experiment is highly reproducible and convenient for data analysis.
It is analyzed by X-ray crystallography or other crystallization techniques, and has good crystallization properties.
It has a short half-life and high clearance.
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