pde9a
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  • Official Full Name
  • PDE9A phosphodiesterase 9A
  • Background
  • Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3, 5monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE10 enzyme belongs to a family of PDEs that hydrolyse both cAMP and cGMP
  • Synonyms
  • PDE9A; phosphodiesterase 9A; high affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A; phosphodiesterase PDE9A21; CGMP-specific 3,5-cyclic phosphodiesterase type 9; HSPDE9A2; FLJ90181
Cat.#:PDE9A-741HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDE9A Protein, MYC/DDK-tagged
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Cat.#:PDE9A-1162HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDE9A, His tagged
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Cat.#:PDE9A-1163HTag:His/GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PDE9A, His & GST tagged
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Cat.#:PDE9A-448HTag:GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Phosphodiesterase 9A, GST-tagged
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Cat.#:PDE9A-550HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDE9A, His-tagged
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Cat.#:PDE9A-551HTag:His/GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PDE9A, His/GST-tagged
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Cat.#:PDE9A-12566MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PDE9A Protein
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Cat.#:PDE9A-4336RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PDE9A Protein
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Cat.#:PDE9A-609HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PDE9A cell lysate
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Cat.#:Kit-1849Tag:
Source (Host):Species:
Product namePDE9A Assay Kit
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Involved Pathway

PDE9A involved in several pathways and played different roles in them. We selected most pathways PDE9A participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE9A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Purine metabolism
PKMB; IMPDH1; FHIT; POLR2B; ITPA; POLR1B; NT5M; CANT1; GUCY1A3; IMPDH1B

Protein Function

PDE9A has several biochemical functions, for example, 3,5-cyclic-GMP phosphodiesterase activity, 3,5-cyclic-nucleotide phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE9A itself. We selected most functions PDE9A had, and list some proteins which have the same functions with PDE9A. You can find most of the proteins on our site.
Function
Related Protein
Function 3,5-cyclic-GMP phosphodiesterase activity
Related Protein PDE6G; PDE6A; PDE11A; PDE6C; PDE6B; PDE9A; PDE5A; PDE6H; PDE10A
Function 3,5-cyclic-nucleotide phosphodiesterase activity
Related Protein PDE4D; PDE8B; PDE10A; PDE5A; PDE9A; PDE6D; PDE11A; PDE3B; PDE5AB; PDE8A
Function metal ion binding
Related Protein ZBTB4; Itgam&Itgb2; STK24; TRPM6; PPM1G; ACACA; FTR67; CYP2C38; ATP2A2B; HPX
Function protein binding
Related Protein EIF3L; PEX5; ARAF; GORAB; SZT2; KRT6A; GOLSYN; KLRC1; WFS1; FLT4

Interacting Protein

PDE9A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE9A here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE9A.
TRIM32; C9orf106; BAG3; LMO2; CLK1