pdia2
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  • Official Full Name
  • protein disulfide isomerase family A, member 2
  • Background
  • Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze;protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996 (PubMed 8561901)).
  • Synonyms
  • PDIA2; protein disulfide isomerase family A, member 2; PDIP, protein disulfide isomerase, pancreatic , protein disulfide isomerase associated 2; protein disulfide-isomerase A2; PDA2; PDI; PDIR; protein disulfide isomerase A2; Rho GDP dissociation inhibi
Cat.#:PDIA2-1481MTag:His
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse PDIA2 Protein (21-527 aa), His-tagged
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Cat.#:PDIA2-1660HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Disulfide Isomerase Family A, Member 2
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Cat.#:PDIA2-1814HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Disulfide Isomerase Family A, Member 2, His-tagged
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Cat.#:PDIA2-672HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Disulfide Isomerase Family A, Member 2
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Cat.#:PDIA2-673HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDIA2, MYC/DDK-tagged
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Cat.#:PDIA2-7047HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDIA2 protein, His & T7-tagged
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Cat.#:PDIA2-12576MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PDIA2 Protein
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Cat.#:Pdia2-28MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Pdia2 protein, His-tagged
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Cat.#:PDIA2-3357RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PDIA2 Protein, His-tagged
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Cat.#:PDIA2-11277ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PDIA2
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Involved Pathway

PDIA2 involved in several pathways and played different roles in them. We selected most pathways PDIA2 participated on our site, such as Statin Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDIA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Statin Pathway
CETP; APOC1; PDIA2; APOC4

Protein Function

PDIA2 has several biochemical functions, for example, disulfide oxidoreductase activity, contributes_to peptidyl-proline 4-dioxygenase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDIA2 itself. We selected most functions PDIA2 had, and list some proteins which have the same functions with PDIA2. You can find most of the proteins on our site.
Function
Related Protein
Function disulfide oxidoreductase activity
Related Protein TXN; GRX2; DNAJC10; COIL; TXNL1; PDIA3; PDIA2; TMX1
Function contributes_to peptidyl-proline 4-dioxygenase activity
Related Protein PDIA2
Function protein binding
Related Protein CDC14B; CCDC42; LINGO1B; SLC7A11; AOC3; MTCH1; ZC4H2; MPG; MAPK10; ACAA2
Function protein disulfide isomerase activity
Related Protein ITGB3; ERP44; PIGK; ERO1LB; ZNF169; QSOX1; TXNDC5; ERO1L; QSOX2; GLRX2
Function steroid binding
Related Protein PGR; AKR1D1; PAQR5B; FAM84B; HSD11B2; ESRRB; PDIA2; NR3C2; ESR1; PGRMC2

Interacting Protein

PDIA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDIA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDIA2.
ABL1; FYN; SRC; NCK1; PLCG1; PIK3R1; CRK; GRB2; P4HB; CALR

PDIA2 Related Articles

Mizuuchi, Y; Aishima, S; et al. Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition. LABORATORY INVESTIGATION 95:193-206(2015).
Fijak, M; Zeller, T; et al. Autoantibodies against protein disulfide isomerase ER-60 are a diagnostic marker for low-grade testicular inflammation. HUMAN REPRODUCTION 29:2382-2392(2014).