pdlim3
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  • Official Full Name
  • PDZ and LIM domain 3
  • Background
  • The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3; ALP; Actinin associated LIM protein; Actinin-associated LIM protein; Alpha actinin 2 associated LIM protein; Alpha-actinin-2-associated LIM protein; DKFZp686L0362; Enigma homolog; PDLI3_HUMAN; PDLIM 3
Cat.#:PDLIM3-822HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDLIM3 Protein, His-tagged
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Cat.#:PDLIM3-1622HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDLIM3, GST-tagged
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Cat.#:PDLIM3-12588MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PDLIM3 Protein
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Cat.#:PDLIM3-4353RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PDLIM3 Protein
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Cat.#:PDLIM3-3360RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PDLIM3 Protein, His-tagged
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Cat.#:PDLIM3-1159CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PDLIM3
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Cat.#:PDLIM3-1324HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PDLIM3 cell lysate
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Protein Function

PDLIM3 has several biochemical functions, for example, cytoskeletal protein binding, protein binding, structural constituent of muscle. Some of the functions are cooperated with other proteins, some of the functions could acted by PDLIM3 itself. We selected most functions PDLIM3 had, and list some proteins which have the same functions with PDLIM3. You can find most of the proteins on our site.
Function
Related Protein
Function cytoskeletal protein binding
Related Protein LDB3; ANXA2; EPB4.1L4A; EPB41L4B; LIN7C; CDK5; ABI1; FARP2; PTPN3; EZRB
Function protein binding
Related Protein RARRES3; SERPINF2; FTCD; BCL2L16; TBK1; PRMT5; GPS1; PEX1; CDKN1B; UBE2C
Function structural constituent of muscle
Related Protein MYL1; ASPH; TPM4; ACTN3; JPH1; MYH11; MYL5; SYNM; SORBS2; MYOM1
Function zinc ion binding
Related Protein ADAM17A; TRIM28; WBP7; PHF21B; MME; ATXN7L3; LMX1A; MAN2A2; ZFP385C; ZDHHC15A

Interacting Protein

PDLIM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDLIM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDLIM3.
ACTN2; RYR1; RANBP2; FHL1; MYPN; MYOZ3; PALLD; MYOZ2; MYOT