Recombinant Human PDLIM3 Protein, His-tagged

• Cat.No.: PDLIM3-822H
• Product Overview: Recombinant human PDLIM3 protein, fused to His tag at N-terminus, was expressed in E. coli.

Specification

• Description: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012]
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
• Molecular Mass: 39.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PDZ and LIM domain 3[ Homo sapiens ]
• Official Symbol: PDLIM3
• Synonyms: ALP
• Gene ID: 27295
• mRNA Refseq: NM_001114107.4
• Protein Refseq: NP_055291
• MIM: 605889
• UniProt ID: Q53GG5