pepd
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  • Official Full Name
  • peptidase D
  • Background
  • This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • PEPD; peptidase D; xaa-Pro dipeptidase; prolidase; MGC95081; Imidodipeptidase; MGC10905; Pep 4; Pep4; PEPD_HUMAN; Peptidase 4; Proline dipeptidase; X pro dipeptidase; X-Pro dipeptidase; aminoacyl-L-proline hydrolase
Cat.#:PEPD-1644HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PEPD, GST-tagged
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Cat.#:PEPD-30835THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PEPD, His-tagged
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Cat.#:PEPD-30836THTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PEPD
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Cat.#:PEPD-766HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PEPD Protein
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Cat.#:PEPD-4376RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PEPD Protein
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Cat.#:PEPD-3550CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PEPD
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Cat.#:PEPD-9872ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PEPD
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Cat.#:PEPD-3297HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PEPD 293 Cell Lysate
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Protein Function

PEPD has several biochemical functions, for example, aminopeptidase activity, dipeptidase activity, manganese ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PEPD itself. We selected most functions PEPD had, and list some proteins which have the same functions with PEPD. You can find most of the proteins on our site.
Function
Related Protein
Function aminopeptidase activity
Related Protein XPNPEP1; LTA4H; METAP1D; LNPEP; XPNPEP3; METAP2; BLMH; CTSL2; METAP2A; ERAP1
Function dipeptidase activity
Related Protein DPEP2; SCRN1; DPEP3; NAALAD2; SCRN2; CNDP2; PEPD; NAALADL1; FOLH1; SCRN3
Function manganese ion binding
Related Protein ARG1; PEPD; HMGCL; MTPAP; XPNPEP3; SLC11A2; LARGE; SOD2; PPM1N; IMPA1
Function metallocarboxypeptidase activity
Related Protein PEPD; AGBL1; CPA1; AGBL5; CPZ; CPA6; AEBP1; CPA2; AGBL2; FOLH1
Function protein binding
Related Protein RHBDD1; SLU7; CTNNA2; PPP2R5D; MOBKL1A; SMR3B; LYVE1; OIP5; AACS; XCL2

Interacting Protein

PEPD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEPD here. Most of them are supplied by our site. Hope this information will be useful for your research of PEPD.
TERF1; PKM; SPP1; ATXN1; glnQ; tig; comEA; q81mj8_bacan; acnA; q8cl08_yerpe

PEPD Related Articles

Lillvis, JH; Kyo, Y; et al. Analysis of positional candidate genes in the AAA1 susceptibility locus for abdominal aortic aneurysms on chromosome 19. BMC MEDICAL GENETICS 12:-(2011).
Wang, TY; Chen, YC; et al. Expression and characterization of the biofilm-related and carnosine-hydrolyzing aminoacylhistidine dipeptidase from Vibrio alginolyticus. FEBS JOURNAL 275:5007-5020(2008).