per3
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  • Official Full Name
  • period homolog 3 (Drosophila)
  • Background
  • This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known.
  • Synonyms
  • PER3; period homolog 3 (Drosophila); period (Drosophila) homolog 3; period circadian protein homolog 3; Cell growth inhibiting gene 13 protein; Circadian clock protein PERIOD 3; GIG13; gPER3; mPer3; Period homolog 3; Period3; hPER3; period 3; period circadian protein 3; growth-inhibiting protein 13; cell growth-inhibiting gene 13 protein
Cat.#:PER3-1646HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PER3, His-tagged
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Cat.#:PER3-12637MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PER3 Protein
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Cat.#:PER3-5487CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PER3
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Cat.#:PER3-9125ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PER3
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Cat.#:PER3-1333HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PER3 cell lysate
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Involved Pathway

PER3 involved in several pathways and played different roles in them. We selected most pathways PER3 participated on our site, such as Circadian rhythm, Circadian entrainment, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with PER3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Circadian rhythm
RBX1; PRKAG1; CUL1; PER3; BHLHE40; NR1D1; CRY2; CLOCK; CRY1; FBXL3
Circadian entrainment
NOS1; RYR1; GRIN1; KCNJ9; GNG13; ITPR3; PLCB3; CALM4; CAMK2D; GRIA1
Herpes simplex infection
TLR9; ALYREF; SKP2; HLA-DRA; TLR2; EEF1DA; C3; SFRS3B; HLA-DRB4; HLA-E

Protein Function

PER3 has several biochemical functions, for example, kinase binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PER3 itself. We selected most functions PER3 had, and list some proteins which have the same functions with PER3. You can find most of the proteins on our site.
Function
Related Protein
Function kinase binding
Related Protein MOB4; DUSP12; CHIA; ABI2; DGKQ; PRDX3; RB1; PER3; TRADD; LDHA
Function protein binding
Related Protein BBS9; RRP8; CPS1; RIC8; NPHP4; RSL24D1; POLR3GL; C1R; STXBP1; GSPT2
Function ubiquitin protein ligase binding
Related Protein CCDC50; ABI2; UBE2O; CCT2; SMAD3; UBE2Z; PML; FBXW7; TP53; NGFR

Interacting Protein

PER3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PER3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PER3.
CHEK2; yscH; yycF; ATM; CCDC88A; CRY2; MIB1; ANKRD36B; AVL9