pfkfb3
Share
  • Official Full Name
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
  • Background
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene.
  • Synonyms
  • PFKFB3; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; iPFK-2; PFK/FBPase 3; 6PF-2-K/Fru-2,6-P2ase 3; renal carcinoma antigen NY-REN-56; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; 6-p
Cat.#:PFKFB3-82912THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PFKFB3, GST-tagged
+Inquiry
Cat.#:PFKFB3-82913THTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PFKFB3, GST-tagged
+Inquiry
Cat.#:PFKFB3-215HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human PFKFB3, GST-tagged
+Inquiry
Cat.#:PFKFB3-24HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PFKFB3 protein, His-tagged
+Inquiry
Cat.#:PFKFB3-518HTag:His|GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PFKFB3 Protein, His & GST-tagged
+Inquiry
Cat.#:PFKFB3-4392RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PFKFB3 Protein
+Inquiry
Cat.#:PFKFB3-12572ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PFKFB3
+Inquiry
Cat.#:PFKFB3-471HCLTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PFKFB3 cell lysate
+Inquiry

Involved Pathway

PFKFB3 involved in several pathways and played different roles in them. We selected most pathways PFKFB3 participated on our site, such as Fructose and mannose metabolism, HIF- signaling pathway, AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PFKFB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Fructose and mannose metabolism
TSTA3; FBP2; ALDOCA; GMDS; GMPPAB; AKR1B8; AKR1B10; PFKFB2A; ALDOCB; MPI
HIF- signaling pathway
CUL2; CAMK2D; PLCG1; RBX1; IFNGR1; CAMK2B; NFKB1; HIF1A; MKNK2; MAP2K2
AMPK signaling pathway
IRS1; G6PC; CREB3L3; PPP2R1A; CPT1A; FBP2; LIPE; FASN; RPS6KB1; PPP2CA

Protein Function

PFKFB3 has several biochemical functions, for example, 6-phosphofructo-2-kinase activity, ATP binding, fructose-2,6-bisphosphate 2-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PFKFB3 itself. We selected most functions PFKFB3 had, and list some proteins which have the same functions with PFKFB3. You can find most of the proteins on our site.
Function
Related Protein
Function 6-phosphofructo-2-kinase activity
Related Protein PFKFB2A; PFKFB1; PFKFB2; PFKFB4; PFKFB4L; PFKFB3
Function ATP binding
Related Protein KIF18A; LATS1; MAP3K5; CDC42BPG; SUCLG1; ATP2C1; CERK; IRAK3; DAK; KTI12
Function fructose-2,6-bisphosphate 2-phosphatase activity
Related Protein C12orf5; PFKFB1; TIGARB; TIGARA; PFKFB3; PFKFB4; PFKFB2

Interacting Protein

PFKFB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PFKFB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PFKFB3.
CUL2; maP3; q81sn0_bacan; q81va8_bacan; ARRB2; ARRB1