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Official Full Name phosphoglucomutase 1
Background The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.
Synonyms PGM1; phosphoglucomutase 1; phosphoglucomutase-1; Glucose phosphomutase 1; GSD14; OTTHUMP00000010519; OTTHUMP00000010520; PGM 1; PGM1_HUMAN; Phosphoglucomutase1
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • SUMO
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Pgm1-4825M Recombinant Mouse Pgm1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human PGM1-6579H Recombinant Human PGM1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human PGM1-716H Recombinant Human PGM1 Protein (1-562 aa), His-SUMO-tagged E.coli His/SUMO
    Human PGM1-2920H Recombinant Human PGM1 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human PGM1-30003TH Recombinant Human PGM1 Wheat Germ N/A
    Human PGM1-3252HCL Recombinant Human PGM1 293 Cell Lysate HEK293 N/A
    Human PGM1-41H Recombinant Human PGM1 protein, His-tagged E.coli His
    Mouse PGM1-12690M Recombinant Mouse PGM1 Protein Mammalian Cell His
    Cynomolgus Monkey PGM1-788C Recombinant Cynomolgus PGM1 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque PGM1-3392R Recombinant Rhesus monkey PGM1 Protein, His-tagged Mammalian Cell His
    Chicken PGM1-3317C Recombinant Chicken PGM1 Mammalian Cell His
    Zebrafish PGM1-11257Z Recombinant Zebrafish PGM1 Mammalian Cell His

    PGM1 involved in several pathways and played different roles in them. We selected most pathways PGM1 participated on our site, such as Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PGM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycolysis / Gluconeogenesis ALDH2.1; ALDOAA; ADH1B; ENO3; BPGM; G6PCA.1; G6PCA.2; GALM; ALDH2.2; ACSS1
    Pentose phosphate pathway TKTL2; GPI1; FBP1A; PGD; GPI; GPIB; RBKS; G6PD; PRPS1A; FBP2
    Galactose metabolism LCT; PGM2; LALBA; GALE; G6PCA.1; UGP2; G6PC3; B4GALT1; GAA; HK3
    Purine metabolism ENPP3; ENTPD2A.1; POLR1D; POLD4; RRM2; PDE7A; PDE5AB; PAICS; NT5C2; IMPDH1A
    Starch and sucrose metabolism UGT2B15; UGT1A6A; GBA3; UGT1A6B; AMY2A; UGDH; UXS1; UGT1A6; AMY2A5; PYGB
    Amino sugar and nucleotide sugar metabolism HEXB; AMDHD2; PMM1; GPIB; NANP; CHIT1; GFPT2; GPI1; GNPDA1; GMDS
    Metabolic pathways HSD17B12; KHK; ALDH3A2A; OTC; SQLE; FUT8A; SAT2B; SCP2A; ACOX3; CES1

    PGM1 has several biochemical functions, for example, magnesium ion binding, phosphoglucomutase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PGM1 itself. We selected most functions PGM1 had, and list some proteins which have the same functions with PGM1. You can find most of the proteins on our site.

    Function Related Protein
    magnesium ion binding RPS6KA3A; RPS6KA4; SIK2; PGM3; NCS1; WEE1; CIB2; PCK1; PPM1B; PTEN
    phosphoglucomutase activity PGM1; PGM2; PGM3
    protein binding PODXL2; PXN; CDCA7L; SIK3; RBFOX2; GMIP; CYTH2; RBP5; HSPBP1; KLF5

    PGM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PGM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PGM1.


    Hata, S; Kanomata, N; et al. Cytologic Appearance of Myospherulosis of the Breast Diagnosed by Fine-Needle Aspirates: A Clinical, Cytological and Immunocytochemical Study of 23 Cases. DIAGNOSTIC CYTOPATHOLOGY 39:177-180(2011).
    Berbic, M; Schulke, L; et al. Macrophage expression in endometrium of women with and without endometriosis. HUMAN REPRODUCTION 24:325-332(2009).

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