PKNOX1 Protein, PBX/knotted 1 homeobox 1


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Official Full Name PBX/knotted 1 homeobox 1
Background Homeobox protein PKNOX1 is a protein that in humans is encoded by the PKNOX1 gene.
Synonyms PKNOX1; PBX/knotted 1 homeobox 1; homeobox protein PKNOX1; PREP1; human homeobox containing protein; Pbx regulating protein 1; PBX/knotted homeobox 1; homeobox protein PREP-1; Pbx regulating protein-1; human homeobox-containing protein; pkonx1c
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PKNOX1-208H Recombinant Human PKNOX1, His-tagged E.coli His
    Human PKNOX1-3148HCL Recombinant Human PKNOX1 293 Cell Lysate HEK293 N/A
    Mouse PKNOX1-12876M Recombinant Mouse PKNOX1 Protein Mammalian Cell His
    Rhesus Macaque PKNOX1-3450R Recombinant Rhesus monkey PKNOX1 Protein, His-tagged Mammalian Cell His

    PKNOX1 involved in several pathways and played different roles in them. We selected most pathways PKNOX1 participated on our site, such as SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PKNOX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    SIDS Susceptibility Pathways PLP1; CC2D1A; LMX1B; ECE1; MAZ; TSPYL1; SNTA1; SCN3B; TPH2; MBD1

    PKNOX1 has several biochemical functions, for example, protein heterodimerization activity, sequence-specific DNA binding, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PKNOX1 itself. We selected most functions PKNOX1 had, and list some proteins which have the same functions with PKNOX1. You can find most of the proteins on our site.

    Function Related Protein
    protein heterodimerization activity ABTB2; IRAK2; ATF2; PDX1; HIST1H4I; WHRN; OSTB; TGFB1; RBP4; HIST1H2AC
    sequence-specific DNA binding HSFX1; HES1; PKNOX1.1; FOXJ1A; LHX8; HOXC6A; HOXB6; HOXB5B; FOXI2; ZNF711
    transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding FOXC1; TEAD2; PKNOX1; POU4F1; BHLHE40; JUN; RFX3; NKX2; MEF2C; MYF5
    transcription factor activity, sequence-specific DNA binding RNF4; MEOX1; FBXW7; ZKSCAN4; HINFP; EF1; ZFP354C; CNOT7; TCF12; PBX1A
    transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ONECUT3; CREB3L3; OVOL2; CEBPA; DLX2; CSRNP3; ATF2; IKZF3; GLIS1; SLAMF7

    PKNOX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PKNOX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PKNOX1.

    PBX2; pp2_dna; MEIS2; PBX1; PBX1; PBX3; q9wmx2-pro_0000037548; mdm2_human_probe; Pbx2; Actb; Pbx1; Mybbp1a

    Tomoeda, M; Yuki, M; et al. Role of Meis1 in mitochondrial gene transcription of pancreatic cancer cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 410:798-802(2011).
    Tran, S; Lamba, P; et al. SMADs and FOXL2 Synergistically Regulate Murine FSH beta Transcription Via a Conserved Proximal Promoter Element. MOLECULAR ENDOCRINOLOGY 25:1170-1183(2011).

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