plekha3
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  • Official Full Name
  • pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
  • Background
  • Binds specifically to phosphatidylinositol-4-phosphate (PtdIns4P), but not to other phosphoinositides.
  • Synonyms
  • PLEKHA3; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3; pleckstrin homology domain-containing family A member 3; FAPP1; four phosphate adaptor protein 1; FAPP 1; FAPP-1; FLJ20067; PH domain-containing family A member 3; Phosphatidylinositol-four-phosphate adapter protein 1; Phosphoinositol 4 phosphate adaptor protein 1; Phosphoinositol 4-phosphate adapter protein 1; PKHA3_HUMAN; Pleckstrin homology domain containing family A (phosphoinositide binding specific) member 3; Pleckstrin homology domain containing family A member 3; PLEKHA 3; OTTHUMP00000205697; four-phosphate-adaptor protein 1; p
Cat.#:PLEKHA3-1776HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLEKHA3, GST-tagged
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Cat.#:PLEKHA3-2910CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PLEKHA3
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Cat.#:PLEKHA3-11423ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PLEKHA3
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Cat.#:PLEKHA3-3117HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PLEKHA3 293 Cell Lysate
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Protein Function

PLEKHA3 has several biochemical functions, for example, 1-phosphatidylinositol binding, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLEKHA3 itself. We selected most functions PLEKHA3 had, and list some proteins which have the same functions with PLEKHA3. You can find most of the proteins on our site.
Function
Related Protein
Function 1-phosphatidylinositol binding
Related Protein PLEKHA2; PICALMB; FRMPD2; EEA1; PLEKHA4; SCARB1; SNX9; CCDC167; WDFY3; PICALM
Function phospholipid binding
Related Protein ANXA9; SERPINB1A; F3; TICAM2; PON1; ANXA5; PAFAH2; APOA5; APOA1; PSD4

Interacting Protein

PLEKHA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLEKHA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLEKHA3.
CSDE1; Csde1

PLEKHA3 Related Articles

Liu, JM; Fukuda, K; et al. Structural Basis of Phosphoinositide Binding to Kindlin-2 Protein Pleckstrin Homology Domain in Regulating Integrin Activation. JOURNAL OF BIOLOGICAL CHEMISTRY 286:43334-43342(2011).
Ooms, LM; Horan, KA; et al. The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease. BIOCHEMICAL JOURNAL 419:29-49(2009).