|Official Full Name||plastin 3|
|Background||Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.|
|Synonyms||PLS3; plastin 3; plastin 3 (T isoform); plastin-3; T plastin; PLST_HUMAN; T fimbrin; T-plastin|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
PLS3 involved in several pathways and played different roles in them. We selected most pathways PLS3 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
PLS3 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PLS3 itself. We selected most functions PLS3 had, and list some proteins which have the same functions with PLS3. You can find most of the proteins on our site.
|actin binding||PFN2L; ACTN2B; ACE; PARK2; EZRB; CAPZA3; TNNT2A; Fert2; VCL; KLHL20|
|calcium ion binding||CCBE1; PKD2; SYT5A; PPP3R1B; CDH8; CD69; LTBP3; SLC25A25A; GPD2; EFCAB12|
PLS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLS3.
ATXN2; EIF1B; NFKB1; HLA-B; VHL; Pafah1b1; IKBKE; Sass6; TNFRSF10D; FTSJ1; 15-deoxy-delta(12,14; MAPK13; PTBP3; MNDA; Actb; GRB2; SLX4; GABARAPL1