POFUT1

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POFUT1

Official Full Name protein O-fucosyltransferase 1
Background This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Synonyms POFUT1; protein O-fucosyltransferase 1; GDP-fucose protein O-fucosyltransferase 1; FUT12; KIAA0180; O Fuc T; O FUT; FUT 12; GDP fucose protein O fucosyltransferase 1; GDP fucose protein O fucosyltransferase1; O FucT 1; O FucT; O FucT1; O-FucT-1; OFuc T; OFucT; OFucT1; OFUT 1; OFUT; OFUT1; OFUT1_HUMAN; Peptide O fucosyltransferase 1; Peptide O fucosyltransferase1; Peptide-O-fucosyltransferase 1; Pofut 1; Protein O fucosyltransferase 1; Protein O fucosyltransferase1; o-fucosyltransferase protein; O-FUT; O-Fuc-T
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human POFUT1-5152H Recombinant Human POFUT1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Pofut1-986M Recombinant Mouse Pofut1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human POFUT1-206H Recombinant Human POFUT1 Protein, His-tagged E.coli His
    Human POFUT1-3057HCL Recombinant Human POFUT1 293 Cell Lysate HEK293 N/A
    Human POFUT1-7213H Recombinant Human POFUT1, His-tagged E.coli His
    Mouse Pofut1-207M Recombinant Mouse Pofut1 Protein, His-tagged E.coli His
    Rat POFUT1-4558R Recombinant Rat POFUT1 Protein Mammalian Cell His
    Chicken POFUT1-5997C Recombinant Chicken POFUT1 Mammalian Cell His
    Zebrafish POFUT1-11738Z Recombinant Zebrafish POFUT1 Mammalian Cell His

    POFUT1 involved in several pathways and played different roles in them. We selected most pathways POFUT1 participated on our site, such as Other types of O-glycan biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with POFUT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Other types of O-glycan biosynthesis B3GALTLA; FUT7; ST3GAL3; FUT9A; ST6GAL2; B4GALT3; ST6GAL1; ST3GAL3B; RFNG; B3GALTLB

    POFUT1 has several biochemical functions, for example, fucosyltransferase activity, peptide-O-fucosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POFUT1 itself. We selected most functions POFUT1 had, and list some proteins which have the same functions with POFUT1. You can find most of the proteins on our site.

    Function Related Protein
    fucosyltransferase activity FT1; B3GNT9-PS; POC1BL; DPY19L1; GALNT18A; FUT2; FUT9A; DPY19L4; FUT9; GLT8D1
    peptide-O-fucosyltransferase activity POFUT1; POFUT2

    POFUT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POFUT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POFUT1.

    AKT2; H2AFX

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