pomt2
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  • Official Full Name
  • protein-O-mannosyltransferase 2
  • Background
  • The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS).
  • Synonyms
  • POMT2; protein-O-mannosyltransferase 2; protein O-mannosyl-transferase 2; A830009D15Rik; AW046274; DKFZp686G10254; Dolichyl phosphate mannose protein mannosyltransferase 2; FLJ22309; POMT 2; Protein O mannosyltransferase 2; Protein O mannosyltransferase; Putative protein O mannosyltransferase; rCG_20643; dolichyl-phosphate-mannose--protein mannosyltransferase 2; MDDGA2; MDDGB2; MDDGC2
Cat.#:POMT2-1857HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human POMT2, GST-tagged
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Cat.#:POMT2-13121MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse POMT2 Protein
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Cat.#:POMT2-3525RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey POMT2 Protein, His-tagged
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Cat.#:POMT2-4102ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish POMT2
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Cat.#:POMT2-3016HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human POMT2 293 Cell Lysate
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Involved Pathway

POMT2 involved in several pathways and played different roles in them. We selected most pathways POMT2 participated on our site, such as Other types of O-glycan biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with POMT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Other types of O-glycan biosynthesis
POFUT1; OGT.1; B4GALT1; FUT9A; ST6GAL1; B3GALTL; ST3GAL3B; GLT25D2; B4GALT3; ST6GAL2

Protein Function

POMT2 has several biochemical functions, for example, contributes_to dolichyl-phosphate-mannose-protein mannosyltransferase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POMT2 itself. We selected most functions POMT2 had, and list some proteins which have the same functions with POMT2. You can find most of the proteins on our site.
Function
Related Protein
Function contributes_to dolichyl-phosphate-mannose-protein mannosyltransferase activity
Related Protein POMT1; POMT2; SDF2L1
Function metal ion binding
Related Protein FDX1L; TNNI3K; ZNF707; CNOT6; ZFP746; HCCS; ZBTB12.2; ZDHHC14; ZFP629; STEAP3

POMT2 Related Articles

Lommel, M; Winterhalter, PR; et al. Protein O-mannosylation is crucial for E-cadherin-mediated cell adhesion. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:21024-21029(2013).
Zhang, P; Hu, HY; et al. Differential glycosylation of alpha-dystroglycan and proteins other than alpha-dystroglycan by like-glycosyltransferase. GLYCOBIOLOGY 22:235-247(2012).