PPA2 Protein, pyrophosphatase (inorganic) 2

PPA2

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PPA2

Official Full Name pyrophosphatase (inorganic) 2
Background The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms PPA2; pyrophosphatase (inorganic) 2; inorganic pyrophosphatase 2, mitochondrial; FLJ20459; HSPC124; PPase2; Pyrophosphatase SID6 306; PPase 2; OTTHUMP00000158985; OTTHUMP00000158986; OTTHUMP00000218513; OTTHUMP00000218514; pyrophosphatase SID6-306; pyrophosphate phospho-hydrolase 2; SID6-306
    • Species :
    • Human
    • Mouse
    • Yeast
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPA2-242H Recombinant Human PPA2 Protein, His-tagged E.coli His
    Human PPA2-2994HCL Recombinant Human PPA2 293 Cell Lysate HEK293 N/A
    Mouse PPA2-13153M Recombinant Mouse PPA2 Protein Mammalian Cell His
    Zebrafish PPA2-11689Z Recombinant Zebrafish PPA2 Mammalian Cell His
    Yeast ppa2-1868Y Recombinant Yeast ppa2, GST-tagged E.coli GST

    PPA2 involved in several pathways and played different roles in them. We selected most pathways PPA2 participated on our site, such as Oxidative phosphorylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oxidative phosphorylation NDUFC2; NDUFS4; SDHC; ATP6V0CB; ATP4B; COX5B2; mt-Atp8; MT-ATP6; COX7B; COX7A3

    PPA2 has several biochemical functions, for example, inorganic diphosphatase activity, magnesium ion binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPA2 itself. We selected most functions PPA2 had, and list some proteins which have the same functions with PPA2. You can find most of the proteins on our site.

    Function Related Protein
    inorganic diphosphatase activity PPA1B; PPA2; PPA1; LHPP; PPA1A; PRUNE
    magnesium ion binding ENO1B; COMTA; GCLC; NEK6; NT5C3L; PPA2; FARS2; RPS6KA2; PDXP; HPRT1L
    protein serine/threonine phosphatase activity PPM1DA; PPM1K; PPM1LB; PPP6C; CDC14AB; TAB1; PPM1N; PPP1R15B; PPP2R2A; ILKAP

    PPA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPA2.

    HTT; 15-deoxy-delta(12,14; ZWINT; MYC; COMT; SIRT4

    Gomez-Garcia, MR; Serrano, A; et al. Expression studies of two paralogous ppa genes encoding distinct Family I pyrophosphatases in marine unicellular cyanobacteria reveal inactivation of the typical cyanobacterial gene. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 295:890-897(2002).
    Rojas-Beltran, JA; Dubois, F; et al. Identification of cystosolic Mg2+-dependent soluble inorganic pyrophosphatases in potato and phylogenetic analysis. PLANT MOLECULAR BIOLOGY 39:449-461(1999).

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