PPP1R3B Protein, protein phosphatase 1, regulatory subunit 3B


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Official Full Name protein phosphatase 1, regulatory subunit 3B
Background This gene encodes the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The encoded protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.
Synonyms PPP1R3B; protein phosphatase 1, regulatory subunit 3B; protein phosphatase 1, regulatory (inhibitor) subunit 3B; protein phosphatase 1 regulatory subunit 3B; FLJ14005; GL; hepatic glycogen targeting subunit; G(L); PP1 subunit R4; PPP1R4; FLJ34675; Hepatic glycogen targeting protein phosphatase 1 regulatory subunit GL; Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL; PPR3B_HUMAN; Protein phosphatase 1 regulatory (inhibitor) subunit 3B; Protein phosphatase 1 regulatory subunit 4; Protein phosphatase 1 subunit 4; Protein phosphatase 1 subunit GL; R4; OTTHUMP00000159678; OTTHUMP00000224512; hepatic glycogen-targeting subunit, G(L)
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP1R3B-1909H Recombinant Human PPP1R3B, GST-tagged E.coli GST
    Human PPP1R3B-2330H Recombinant Human PPP1R3B, His-tagged E.coli His
    Human PPP1R3B-2935HCL Recombinant Human PPP1R3B 293 Cell Lysate HEK293 N/A
    Mouse PPP1R3B-13238M Recombinant Mouse PPP1R3B Protein Mammalian Cell His
    Rat PPP1R3B-4626R Recombinant Rat PPP1R3B Protein Mammalian Cell His
    Zebrafish PPP1R3B-11984Z Recombinant Zebrafish PPP1R3B Mammalian Cell His

    PPP1R3B involved in several pathways and played different roles in them. We selected most pathways PPP1R3B participated on our site, such as Insulin signaling pathway, Insulin resistance, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1R3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Insulin signaling pathway GYS1; PPP1CAA; PHKA1; G6PC; PHKA2; PRKAR2B; PHKG1A; PRKAA2; LIPE; PRKAR2AA
    Insulin resistance NR1H3; PRKAG3B; CREB3L3A; RPS6KB2; SLC2A4; PPP1R3DA; PPP1CAB; RPS6KB1B; PCK1; SLC27A4

    PPP1R3B has several biochemical functions, for example, enzyme binding, phosphoprotein phosphatase activity, protein phosphatase regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1R3B itself. We selected most functions PPP1R3B had, and list some proteins which have the same functions with PPP1R3B. You can find most of the proteins on our site.

    Function Related Protein
    enzyme binding U2AF2; APOA1; HIST1H2AL; UGT1A3; GNB2L1; USF1; MAPK14; GOLPH3; DDX5; HDAC10
    phosphoprotein phosphatase activity PPP3CB; CPPED1; CDC14AA; CTDSPL2; CTDSPL2A; PTPN4A; PTPRZ1; MTM1; PTPN2A; ACP2
    protein phosphatase regulator activity PPP1R3CB; PPP4R4; SHOC2; PPP1R3CA; PPP1R3B; PPP1R3C

    PPP1R3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1R3B here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1R3B.


    Lin, YC; Chang, PF; et al. Genetic variants in GCKR and PNPLA3 confer susceptibility to nonalcoholic fatty liver disease in obese individuals. AMERICAN JOURNAL OF CLINICAL NUTRITION 99:869-874(2014).
    Hernaez, R; McLean, J; et al. Association Between Variants in or Near PNPLA3, GCKR, and PPP1R3B With Ultrasound-Defined Steatosis Based on Data From the Third National Health and Nutrition Examination Survey. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY 11:1183-U203(2013).

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