Recombinant Human PPP1R3B, His-tagged

• Cat.No.: PPP1R3B-2330H
• Product Overview: Recombinant human PPP1R3B protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Description: PPP1R3B is the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
• Molecular Mass: 35.1 kDa
• Protein length: 308aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMMAVDIE YRYNCMAPSL RQERFAFKIS PKPSKPLRPC IQLSSKNEAS GMVAPAVQEK KVKKRVSFAD NQGLALTMVK VFSEFDDPLD MPFNITELLD NIVSLTTAES ESFVLDFSQP SADYLDFRNR LQADHVCLEN CVLKDKAIAG TVKVQNLAFE KTVKIRMTFD TWKSYTDFPC QYVKDTYAGS DRDTFSFDIS LPEKIQSYER MEFAVYYECN GQTYWDSNRG KNYRIIRAEL KSTQGMTKPH SGPDLGISFD QFGSPRCSYG LFPEWPSYLG YEKLGPYY
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: PPP1R3B protein phosphatase 1, regulatory subunit 3B [ Homo sapiens ]
• Official Symbol: PPP1R3B
• Synonyms: PPP1R3B; protein phosphatase 1, regulatory subunit 3B; protein phosphatase 1, regulatory (inhibitor) subunit 3B; protein phosphatase 1 regulatory subunit 3B; FLJ14005; GL; hepatic glycogen targeting subunit; G(L); PP1 subunit R4; PPP1R4; hepatic glycogen-targeting subunit, G(L); protein phosphatase 1 regulatory subunit 4; hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL; PTG; FLJ34675
• Gene ID: 79660
• mRNA Refseq: NM_001201329
• Protein Refseq: NP_001188258
• MIM: 610541
• UniProt ID: Q86XI6
• Chromosome Location: 8p23.1
• Pathway: Insulin signaling pathway, organism-specific biosystem; Insulin signaling pathway, conserved biosystem