PPP2R2C Protein, protein phosphatase 2, regulatory subunit B, gamma


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Official Full Name protein phosphatase 2, regulatory subunit B, gamma
Background The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform , protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform; IMYPNO; MGC33570; PP2A subunit B isoform gamma; PR52; PR55G; 2ABG_HUMAN; B55 gamma; Gamma isoform of regulatory subunit B55 protein phosphatase 2; IMYPNO 1; IMYPNO1; Phosphoprotein phosphatase 2A BR gamma regulatory chain; PP2A subunit B B gamma isoform; PP2A subunit B B55 gamma isoform; PP2A subunit B isoform B55-gamma; PP2A subunit B isoform PR55-gamma; PP2A subunit B isoform R2-gamma; PP2A subunit B PR55 gamma isoform; PP2A subunit B R2 gamma isoform; PPP2R2C protein; PR 52; PR 55G; Protein phosphatase 2 (formerly 2A) regulatory subunit B gamma isoform; Protein phosphatase 2 regulatory subunit B gamma; Protein phosphatase 2 regulatory subunit B gamma isoform; Protein phosphatase 2A1 B gamma subunit; Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform; OTTHUMP00000115505; OTTHUMP00000115506; OTTHUMP00000217568; OTTHUMP00000217634; OTTHUMP00000217635; PP2A, subunit B, B-gamma isoform; PP2A, subunit B, R2-gamma isoform; PP2A, subunit B, B55-gamma isoform; PP2A, s; B55-GAMMA
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP2R2C-2762H Recombinant Human PPP2R2C Protein (1-447 aa), His-Myc-tagged Insect Cell His/Myc
    Human PPP2R2C-1403HCL Recombinant Human PPP2R2C cell lysate N/A
    Human PPP2R2C-1917H Recombinant Human PPP2R2C, GST-tagged E.coli GST
    Human PPP2R2C-27932TH Recombinant Human PPP2R2C Wheat Germ N/A
    Mouse PPP2R2C-13255M Recombinant Mouse PPP2R2C Protein Mammalian Cell His
    Rat PPP2R2C-4636R Recombinant Rat PPP2R2C Protein Mammalian Cell His
    Rhesus Macaque PPP2R2C-3572R Recombinant Rhesus monkey PPP2R2C Protein, His-tagged Mammalian Cell His

    PPP2R2C involved in several pathways and played different roles in them. We selected most pathways PPP2R2C participated on our site, such as mRNA surveillance pathway, Sphingolipid signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP2R2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    mRNA surveillance pathway PAPOLB; PPP1CAA; ETF1A; WIBG; SMG1; PPP1CA; NCBP1; PPP2R5D; SRRM1; SMG7
    Sphingolipid signaling pathway GNAI3; PLCB3; LASS5; RAC3; MAPK9; MAPK3; NOS3; MS4A2; SGPL1; MAPK13
    PIK-Akt signaling pathway ITGA5; SYK; PCK1; PHLPP1; FGF18; TSC1; PRLR; BCL2; YWHAB; IL4
    AMPK signaling pathway INS1; MTOR; PPP2R5D; MAP3K7; PFKFB3; RAB10; PRKAB2; CREB3L1; FASN; TSC1
    Adrenergic signaling in cardiomyocytes TNNC1; ADRB1; MYL2; ADRA1D; CACNA2D1; PPP2R5E; CREB3L4; ATP1A2; CREB3L3L; AKT1
    Hippo signaling pathway TGFBR1; CTNNA3; WNT9A; PRKCI; PPP2R2B; BBC3; TGFBR2; SCRIB; BMPR1B; BMPR1A
    Tight junction RRAS2; PRKCI; MYLPFA; MYH1C; MYHC4; MYH9A; CLDN3; MLLT4; MYH4; PPP2CB
    Dopaminergic synapse COMT; DRD2; GNAQ; PRKCA; ARNTL; GNG4; KCNJ3; PPP2R1B; CAMK2A; PRKCB
    Chagas disease (American trypanosomiasis) PIK3CA; PIK3CG; MYD88; MAPK3; TGFB3; IL6; BDKRB2; TLR9; TGFBR2; SERPINE1
    Hepatitis C OAS2; IFNA13; SOS1; IFNA14; EIF2AK4; IKBKG; PIK3CA; SCARB1; MAPK8; PIK3R1

    PPP2R2C has several biochemical functions, for example, protein binding, protein phosphatase type 2A regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP2R2C itself. We selected most functions PPP2R2C had, and list some proteins which have the same functions with PPP2R2C. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TPCN2; PUF60; ARVCF; FCN3; TMPRSS15; LC3; SMN2; CCDC53; KLKB1; KIF6
    protein phosphatase type 2A regulator activity PPP2R2C; PPP2R3A; PPP2R4; PPME1; ENSA; PPP2R5CB; PPP2R1B; PPP2R2CA; ARPP19; PPP2R2D

    PPP2R2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP2R2C here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP2R2C.


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