ppp6c
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  • Official Full Name
  • protein phosphatase 6, catalytic subunit
  • Background
  • This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression.
  • Synonyms
  • PPP6C; protein phosphatase 6, catalytic subunit; serine/threonine-protein phosphatase 6 catalytic subunit; PP6; serine/threonine protein phosphatase catalytic subunit; PP6C; FLJ92648; MGC12249
Cat.#:PPP6C-1928HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP6C, His-tagged
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Cat.#:PPP6C-29541THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PPP6C
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Cat.#:PPP6C-13276MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PPP6C Protein
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Cat.#:PPP6C-4646RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PPP6C Protein
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Cat.#:PPP6C-3597CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PPP6C
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Cat.#:PPP6C-11238ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PPP6C
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Cat.#:PPP6C-1407HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPP6C cell lysate
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Involved Pathway

PPP6C involved in several pathways and played different roles in them. We selected most pathways PPP6C participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP6C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Asparagine N-linked glycosylation
SEC22A; DERL2; DDOST; MCFD2; SEC16B; AREG; YKT6; CTSZ; MPDU1A; ST8SIA2
COPII (Coat Protein 2) Mediated Vesicle Transport
SERPINA1L; NSFB; SEC23A; TRAPPC2L; SEC23IP; PPP6R1; AREG; CNIH2; CTSZ; NAPG
ER to Golgi Anterograde Transport
SEC22A; USO1; TMED10; SEC16B; TRAPPC6BL; SEC23IP; SERPINA1L; CNIH; AREG; BET1
Membrane Trafficking
TMED10; SEC22A; GJB3; BLOC1S3; SNF8; TMED2; TRAPPC6B; COPE; DTNBP1; CNIH3
Metabolism of proteins
PIGK; DHPS; PREB; PAPPA; TOMM40; DPH1; IGFBP4; ALG2; TRAPPC4; EIF5
Post-translational protein modification
SLC35A1; NAPAB; ADAMTS10; CNIH; CNIH3; WDR85; B3GNT8; MAN1A2; SPON1; MGAT4B
Transport to the Golgi and subsequent modification
ANKRD28; TRAPPC2; TRAPPC2L; NAPG; YKT6; MGAT4B; MCFD2; TRAPPC10; TRAPPC5; SEC22A
Vesicle-mediated transport
PUM1; CX27.5; SNAPIN; MYO1C; GJA5; SNX9; STXBP3; PLDN; DTNBP1B; GAK

Protein Function

PPP6C has several biochemical functions, for example, metal ion binding, protein binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP6C itself. We selected most functions PPP6C had, and list some proteins which have the same functions with PPP6C. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein RNF180; EGLN1B; SETDB1A; ZBED4; TGM4; SGSH; ZIC5; ZNF177; NRP1A; CYP2Y3
Function protein binding
Related Protein SCAMP2; CINP; ZFP36; RND3; DYRK4; TSPAN4; PSENEN; CXCL14; JDP2; IL5
Function protein serine/threonine phosphatase activity
Related Protein PPM1LB; PTEN; PPM1L; PPM1F; PP2D1; PHLPP2; PPP2R1A; CDKN3; PPM1A; PPM1B

Interacting Protein

PPP6C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP6C here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP6C.
IGBP1; PPP6R1

PPP6C Related Articles

Liu, Y; Zhang, LW; et al. DNA-PKcs Deficiency Inhibits Glioblastoma Cell-Derived Angiogenesis After Ionizing Radiation. JOURNAL OF CELLULAR PHYSIOLOGY 230:1094-1103(2015).
Crajoinas, RO; Pessoa, TD; et al. Changes in the activity and expression of protein phosphatase-1 accompany the differential regulation of NHE3 before and after the onset of hypertension in spontaneously hypertensive rats. ACTA PHYSIOLOGICA 211:395-408(2014).