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PPP6R3

  • Official Full Name

    protein phosphatase 6, regulatory subunit 3

  • Overview

    Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits;by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the;holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725);(Stefansson and Brautigan, 2006 (PubMed 16769727)).
  • Synonyms

    PPP6R3; protein phosphatase 6, regulatory subunit 3; C11orf23, chromosome 11 open reading frame 23 , SAPS domain family, member 3 , SAPS3; serine/threonine-protein phosphatase 6 regulatory subunit 3; DKFZp781E2374; DKFZp781E17107; DKFZp781O2362; FLJ11058; FLJ43065; KIAA1558; MGC125711; MGC125712; PP6R3; SAP190; SAPL; SAPLa; sporulation induced transcript 4 associated protein; C11orf23; Chromosome 11 open reading frame 23; PP6R3_HUMAN; Protein phosphatase 6 regulatory subunit 3; SAPS domain family member 3; SAPS domain family, member 3; Sporulation induced transcript 4 associated protein SAPL; Sporulation-induced transcript 4-associated protein SAPL; SAPS3;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPP6R3-2066HCL Recombinant Human SAPS3 293 Cell Lysate HEK293 N/A
Mouse PPP6R3-13279M Recombinant Mouse PPP6R3 Protein Mammalian Cell His
Mouse Ppp6r3-5087M Recombinant Mouse Ppp6r3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PPP6R3-7048M Recombinant Mouse PPP6R3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PPP6R3-7048M-B Recombinant Mouse PPP6R3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PPP6R3-10082Z Recombinant Zebrafish PPP6R3 Mammalian Cell His
Chicken PPP6R3-2850C Recombinant Chicken PPP6R3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PPP6R3 involved in several pathways and played different roles in them. We selected most pathways PPP6R3 participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP6R3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Asparagine N-linked glycosylationPPP6R3;SEC22C;NAPB;MPDU1B;SERPINA1L;MAN1A2;CTSZ;TMED2;ST6GALNAC1.2
COPII (Coat Protein 2) Mediated Vesicle TransportLMAN2L;SEC16B;NAPAB;TRAPPC10;TRAPPC9;NSFA;SEC24A;CNIH3;GOLGA2
ER to Golgi Anterograde TransportCNIH2;CTSZ;YKT6;MIA3;TRAPPC6BL;TRAPPC6B;NAPAA;SEC16B;TRAPPC3
Membrane TraffickingDAB2;BLOC1S3;CNIH;TMED10;EXOC8;TFG;TERFA;STAM2;PICALM
Metabolism of proteinsTOMM6;DDX11;WDR85;EEF1G;FBXW2;TOMM22;SEC22A;CNIH2;NAPAA
Post-translational protein modificationTRAPPC3;THSD1;ALG14;MUC1;LMAN2L;NSMCE4A;SCFD1;ADAMTS10;STT3A
Transport to the Golgi and subsequent modificationTRAPPC10;TRAPPC9;YKT6;TRAPPC6B;TMED10;TRAPPC2L;ANKRD28;NAPB;PPP6R3
Vesicle-mediated transportCLVS2;TPD52;NAPG;CLVS1;GJB7;TRAPPC2;TBC1D8B;COPG;NFX1

PPP6R3 has several biochemical functions, for example, protein binding, protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP6R3 itself. We selected most functions PPP6R3 had, and list some proteins which have the same functions with PPP6R3. You can find most of the proteins on our site.

Function Related Protein
protein bindingHSPE1;FOSL2;FTCD;DAO;HCK;SIAH2;SERPINA1A;C14orf135;RNF146
protein phosphatase bindingJUP;JAK1;CSK;Itga10&Itgb1;MET;SKAP1;JUPA;CSF1R;AP3B1

PPP6R3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP6R3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP6R3.

PPP6C; ANKRD28; TERF2IP; NFKBIE; USP49; TNIP3; USP36; USP21; yscO; TINF2; mdm2_human_probe

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