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Official Full Name protein kinase C, eta
Background Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.
Synonyms PRKCH; protein kinase C, eta; protein kinase C eta type; PKC-L; nPKC-eta; protein kinase C-eta; MGC93383
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • Flag
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PRKCH-18H Recombinant Human PRKCH protein, His-tagged E.coli His
    Human PRKCH-19H Recombinant Human PRKCH protein, GST/His-tagged Insect Cell GST/His
    Human PRKCH-2855HCL Recombinant Human PRKCH 293 Cell Lysate HEK293 N/A
    Human PRKCH-28938TH Recombinant Human PRKCH N/A
    Human PRKCH-403H Recombinant Human Protein Kinase C, Eta, GST-tagged, Active Sf9 Insect Cell GST
    Human PRKCH-71H Recombinant Human PRKCH protein, Flag-tagged, Biotinylated Insect Cell Flag
    Human PRKCH-8457H Recombinant Human PRKCH Sf9 Insect Cell N/A
    Mouse PRKCH-13367M Recombinant Mouse PRKCH Protein Mammalian Cell His
    Rat PRKCH-4681R Recombinant Rat PRKCH Protein Mammalian Cell His

    PRKCH involved in several pathways and played different roles in them. We selected most pathways PRKCH participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKCH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Vascular smooth muscle contraction ROCK1; PLA2G4C; PPP1CAB; ADCY1B; PLA2G6; PRKCB; RAF1B; PRKACBB; PRKACG; ACTA2
    Tight junction CLDN15A; PPP2R2BB; CLDN5; MYL9A; CRB3; HRASB; CLDN20; MYH11A; HCLS1; MPP5
    Inflammatory mediator regulation of TRP channels CYP2J6; P2RY2; PIK3CG; PRKCG; PRKCD; NTRK1; PRKCQ; SRC; KLK1B4; CALML3

    PRKCH has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKCH itself. We selected most functions PRKCH had, and list some proteins which have the same functions with PRKCH. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding CAMK1D; TARS; RAD17; CDK4; NUAK2; MASTL; SUPV3L1; STK3; SLC22A5; HSPA12A
    Ral GTPase binding EXOC8; RNF41; FLNA; RAB34; MYO1C; LSM2; PIH1D2; PRKCH; RALBP1; USP33
    calcium-independent protein kinase C activity PRKCE; PRKCD; PRKCH
    enzyme binding SLC27A2; YWHAE; PEX5; MAPK14; TSPAN17; NOXA1; EGLN1; CTNNB1; BRCA1; PHKG2
    metal ion binding CRYAA; NRXN1; GFI1AB; LIMCH1B; PRKD3; TATDN1; PHOSPHO2; NT5C2L1; ADARB2; KCNIP1B
    protein kinase C activity PKN1; PRKD1; PRKD2; PRKCE; PRKCB; PRKCBB; PRKCD; PRKCI; PRKCZ; PKN2

    PRKCH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKCH here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKCH.

    ndb25_parsc; HSP90AB1; glpD; ZBTB8OS

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