prkg2
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  • Official Full Name
  • protein kinase, cGMP-dependent, type II
  • Synonyms
  • PRKG2; protein kinase, cGMP-dependent, type II; cGMP-dependent protein kinase 2; cGKII; PRKGR2; cGK2; cGK 2; cGMP-dependent protein kinase II
Cat.#:PRKG2-4685RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PRKG2 Protein
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Cat.#:Prkg2-603RTag:N/A
Source (Host):Sf 9 Insect cellsSpecies:Rat
Product nameRecombinant Rat Protein Kinase, cGMP-dependent, Type II
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Cat.#:PRKG2-6006ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PRKG2
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Cat.#:PRKG2-1089HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase, CGMP-Dependent, Type II, GST-tagged
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Cat.#:PRKG2-2849HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PRKG2 293 Cell Lysate
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Involved Pathway

Prkg2 involved in several pathways and played different roles in them. We selected most pathways Prkg2 participated on our site, such as cGMP-PKG signaling pathway, Gap junction, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with Prkg2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
cGMP-PKG signaling pathway
PPP1CC; ATP1A2; PRKCE; PPP3CC; MAP2K1; CREB3L1; KCNJ8; IRS4; PIK3R2; SLC8A2
Gap junction
GNA11; TUBA1L; PLCB3; HTR2B; ADCY2B; GNAI1; TUBA7L; HTR2A; MAP2K2; TUBA3D
Platelet activation
RAP1B; TBXAS1; MYLK; FGA; PPP1CA; PIK3R5; TLN1; P2RX1; GNAI2; APBB1IP
Circadian entrainment
GNG5; GNAO1; GNB4; PRKACG; MAPK1; Adcy4; AKR1C1; GNG8; GNB1; GNG11
Long-term depression
HRAS; NOS1; IGF1R; MAPK3; GNAO1; PRKCG; RAF1; GRM1; PRKG2; PLA2G4A
Olfactory transduction
ARRB1; CLCA1; OLFR15; PRKACB; OR5V1; OR4D2; OLFR477; OLFR482; OLFR186; OR56A1
Regulation of lipolysis in adipocytes
NPY; IRS4; AKT1; PRKACG; LIPE; INS1; NPR1; FABP4; IRS2; PIK3CG
Renin secretion
AQP1; PDE1C; PRKACG; CALML5; PPP3CB; ORAI1; GNAI1; CALM3; CALM4; ACE
Salivary secretion
LYZ1; PMAP-36; ATP2B4; CALM3; AMY1A; HTN1; CST1; BEST2; CST3; LYZ2

Protein Function

Prkg2 has several biochemical functions, for example, ATP binding, cGMP binding, cGMP-dependent protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Prkg2 itself. We selected most functions Prkg2 had, and list some proteins which have the same functions with Prkg2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein MCMDC2; BMPR1BA; EPHB3; MAP3K9; RBM4.3; ATPBD4; NME6; CCT5; MAST4; MAK
Function cGMP binding
Related Protein CNGA4; PDE6G; CNGA2; CNGA3; PDE6C; PDE11A; PRKG1A; PDE6H; PRKG1; PDE2A
Function cGMP-dependent protein kinase activity
Related Protein PRKG2; PRKG1; PRKG1A
Function protein homodimerization activity
Related Protein HOMER2; CRYBA1; TIMM9; DAXX; EIF2AK3; ALDH1A3; PLD6; OLFM4; MTUS2; DGAT2
Function protein kinase activity
Related Protein HIPK3A; SYK; PAN3; TRIM24; PRKCHA; COL4A3BP; TSSK1; PDK3; MAPK14B; POMK

Interacting Protein

Prkg2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Prkg2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Prkg2.
saicar; PKM; CDKL5; HSP90AB1