| Description : |
This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The membrane-bound protein is a regulator of intestinal secretion, bone growth and renin secretion. Alternate splicing results in multiple transcript variants encoding distinct isoforms whose regulatory N-termini differ in length but whose C-terminal catalytic domains are identical. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
87.3 kDa |
| AA Sequence : |
MGNGSVKPKHSKHPDGHSGNLTTDA LRNKVTELERELRRKDAEIQEREYH LKELREQLSKQTVAIAELTEELQNK CIQLNKLQDVVHMQGGSPLQASPDK VPLEVHRKTSGLVSLHSRRGAKAGV SAEPTTRTYDLNKPPEFSFEKARVR KDSSEKKLITDALNKNQFLKRLDPQ QIKDMVECMYGRNYQQGSYIIKQGE PGNHIFVLAEGRLEVFQGEKLLSSI PMWTTFGELAILYNCTRTASVKAIT NVKTWALDREVFQNIMRRTAQARDE QYRNFLRSVSLLKNLPEDKLTKIID CLEVEYYDKGDYIIREGEEGSTFFI LAKGKVKVTQSTEGHDQPQLIKTLQ KGEYFGEKALISDDVRSANIIAEEN DVACLVIDRETFNQTVGTFEELQKY LEGYVANLNRDDEKRHAKRSMSNWK LSKALSLEMIQLKEKVARFSSSSPF QNLEIIATLGVGGFGRVELVKVKNE NVAFAMKCIRKKHIVDTKQQEHVYS EKRILEELCSPFIVKLYRTFKDNKY VYMLLEACLGGELWSILRDRGSFDE PTSKFCVACVTEAFDYLHRLGIIYR DLKPENLILDAEGYLKLVDFGFAKK IGSGQKTWTFCGTPEYVAPEVILNK GHDFSVDFWSLGILVYELLTGNPPF SGVDQMMTYNLILKGIEKMDFPRKI TRRPEDLIRRLCRQNPTERLGNLKN GINDIKKHRWLNGFNWEGLKARSLP SPLQRELKGPIDHSYFDKYPPEKGM PPDELSGWDKDFTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
