• Official Full Name
  • paired related homeobox 2
  • Background
  • The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.
  • Synonyms
  • PRRX2; paired related homeobox 2; paired mesoderm homeobox protein 2; PMX2; PRX2; Paired related homeobox protein 2; Paired-related homeobox protein 2; Predicted NUP98/PRRX2 fusion protein; PRRX2_HUMAN; PRX 2; PRX-2; OTTHUMP00000022344; OTTHUMP00000245229; paired-like homeodomain protein PRX2
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PRRX2
Source (Host):Species:Human
Product nameRecombinant Human PRRX2 cell lysate

Protein Function

PRRX2 has several biochemical functions, for example, sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRRX2 itself. We selected most functions PRRX2 had, and list some proteins which have the same functions with PRRX2. You can find most of the proteins on our site.
Related Protein
Function sequence-specific DNA binding
Related Protein DMRTA2; LHX3; NKX1.2LB; IRX6A; HOXC4A; EN2; NR1H4; ERG; HES1; GZF1
Function transcription factor activity, sequence-specific DNA binding
Related Protein GBX2; ZNF613; MEF2A; ZNF263; HSF5; HOXA6; NR4A2A; SIX2; CITED1; HOXC8