This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined.
PRSS16 has several biochemical functions, for example, serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRSS16 itself. We selected most functions PRSS16 had, and list some proteins which have the same functions with PRSS16. You can find most of the proteins on our site.
Function serine-type peptidase activity
Related Protein CFD; HTRA1; EGFBP2; TMPRSS11E; KLK10; F9B; KLK1B3; PRSS16; PRSS3; SEC11C