PSMD11 Protein, proteasome (prosome, macropain) 26S subunit, non-ATPase, 11


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Official Full Name proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.
Synonyms PSMD11; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11; 26S proteasome non-ATPase regulatory subunit 11; MGC3844; p44.5; Rpn6; S9; 26S proteasome regulatory subunit 9; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit p44.5
    • Species :
    • Cynomolgus Monkey
    • Human
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PSMD11-2027H Recombinant Human PSMD11, His-tagged E.coli His
    Human PSMD11-2470H Recombinant human PSMD11, His-tagged E.coli His
    Human PSMD11-2754HCL Recombinant Human PSMD11 293 Cell Lysate HEK293 N/A
    Cynomolgus Monkey PSMD11-822C Recombinant Cynomolgus PSMD11 Protein, His-tagged Mammalian Cell His

    PSMD11 involved in several pathways and played different roles in them. We selected most pathways PSMD11 participated on our site, such as Proteasome, Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteasome PSMA7; POMP; SHFM1; PSMA3; PSMB5; PSMB7; PSMD11A; PSMB11; PSMD8; PSMD1
    Epstein-Barr virus infection HSPA1L; SNW1; MAPK8; HSPB1; SHFM1; NEDD4; TBPL1; CD58; TAB1; POLR2A

    PSMD11 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD11 itself. We selected most functions PSMD11 had, and list some proteins which have the same functions with PSMD11. You can find most of the proteins on our site.

    Function Related Protein
    protein binding SMARCE1; PALLD; NAT10; LARP7; RNF216; GPS2; PMP2; ARHGEF6; CD2AP; PPIG

    PSMD11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD11 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD11.

    UCHL5; PSMD14; PSMD10; VCAM1; PRMT6; env; LRRK2; NFKB2; PSMC4

    Qi, TG; Zhang, W; et al. Proteomic Profiling Identified Multiple Short-lived Members of the Central Proteome as the Direct Targets of the Addicted Oncogenes in Cancer Cells. MOLECULAR & CELLULAR PROTEOMICS 13:49-62(2014).
    Zhao, B; Velasco, K; et al. The ubiquitin specific protease-4 (USP4) interacts with the S9/Rpn6 subunit of the proteasome. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 427:490-496(2012).

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