psmd11
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  • Official Full Name
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
  • Background
  • The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.
  • Synonyms
  • PSMD11; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11; 26S proteasome non-ATPase regulatory subunit 11; MGC3844; p44.5; Rpn6; S9; 26S proteasome regulatory subunit 9; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit p44.5
Cat.#:PSMD11-2027HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PSMD11, His-tagged
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Cat.#:PSMD11-2470HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant human PSMD11, His-tagged
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Cat.#:PSMD11-822CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PSMD11 Protein, His-tagged
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Cat.#:PSMD11-2754HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PSMD11 293 Cell Lysate
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Involved Pathway

PSMD11 involved in several pathways and played different roles in them. We selected most pathways PSMD11 participated on our site, such as Proteasome, Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Proteasome
PSMD6; SHFM1; PSMD4; PSMB9B; PSMD8; PSMD2; PSMD13; PSMD7; PSMA5; PSMC2
Epstein-Barr virus infection
CD40; HDAC5; PRKACA; TRAF6; TNFAIP3; HDAC1; POLR3D; MDM2; SKP2; HLA-DQA2

Protein Function

PSMD11 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD11 itself. We selected most functions PSMD11 had, and list some proteins which have the same functions with PSMD11. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein PRKDC; UBXN8; WDR61; BCL2L1; STUB1; CYB5R1; SYT17; GFPT2; SARM1; OPA1

Interacting Protein

PSMD11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD11 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD11.
UCHL5; PSMD14; PSMD10; VCAM1; PRMT6; env; LRRK2; NFKB2; PSMC4

PSMD11 Related Articles

Qi, TG; Zhang, W; et al. Proteomic Profiling Identified Multiple Short-lived Members of the Central Proteome as the Direct Targets of the Addicted Oncogenes in Cancer Cells. MOLECULAR & CELLULAR PROTEOMICS 13:49-62(2014).
Zhao, B; Velasco, K; et al. The ubiquitin specific protease-4 (USP4) interacts with the S9/Rpn6 subunit of the proteasome. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 427:490-496(2012).