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Official Full Name paxillin
Background This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the;extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been;described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well;as physiological properties (PMID:9054445).
Synonyms PXN; paxillin; FLJ16691
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    • N/A
    • Trx
    • S
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PXN-029H Recombinant Human PXN Protein, Trx, His and S-tags-tagged E.coli Trx/His/S
    Human PXN-030H Recombinant Human PXN Protein, His-tagged E.coli His
    Human PXN-2083H Recombinant Human PXN, His-tagged E.coli His
    Human PXN-2413H Recombinant Human Paxillin, GST-tagged E.coli GST
    Human PXN-2651HCL Recombinant Human PXN 293 Cell Lysate HEK293 N/A
    Human PXN-29060TH Recombinant Human PXN E.coli N/A
    Mouse Pxn-1874M Recombinant Mouse Pxn protein, His & T7-tagged E.coli His/T7
    Rat Pxn-1875R Recombinant Rat Pxn protein, His & T7-tagged E.coli His/T7
    Rat PXN-4856R Recombinant Rat PXN Protein Mammalian Cell His
    Chicken PXN-6542C Recombinant Chicken PXN Mammalian Cell His

    PXN involved in several pathways and played different roles in them. We selected most pathways PXN participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PXN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chemokine signaling pathway GNB4; ARRB1; PAK1; CXCL3; STAT2; GNG11; FGR; CXCL8; CDC42; HCK
    VEGF signaling pathway PLCG1; PLA2G4D; VEGFAB; PLA2G4F; PLCG2; MAPKAPK3; PIK3R1; MAPK12; MAP2K2; MAPK12A
    Leukocyte transendothelial migration ACTN3; MYL12A; PIK3CB; MYL7; PIK3CD; MMP2; MAPK13; NIPAL1; PLCG2; ARHGAP5
    Regulation of actin cytoskeleton VAV1; CFL2; RASSF7; MYL12.1; SSH2; PIP5K1BB; ARHGEF6; SCIN; GNG12; ABI2
    Bacterial invasion of epithelial cells CTNNA1; PIK3R2; CAV1; MET; WASF1; PIK3R5; VCL; PIK3R1; ARPC5L; ELMO1
    Viral carcinogenesis SP100; BAK1; CCNA1; HLA-E; NFKBIA; EIF2AK2; PRKACA; HDAC7; ACTN3; HRAS
    Proteoglycans in cancer VAV2; WNT4; ITGA2; FZD7; HSPB2; ITGB1; LUM; COL21A1; NANOG; PIK3CG

    PXN has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PXN itself. We selected most functions PXN had, and list some proteins which have the same functions with PXN. You can find most of the proteins on our site.

    Function Related Protein
    BH4 domain binding PXN
    beta-catenin binding TCF7L1A; SMAD7; CDH24; BTRC; PXN; KDM6B; PARK2; SLC9A3R2; SMAD3; NUMB
    integrin binding CTGFA; VCAM1; IGF1; ADAM9; JAM3; WISP1; ADAM25; ADAM15; Tcam1; WISP1B
    protein binding CSRNP1; PKN3; VSTM2L; ATRIP; RCN1; FN1; RAB11FIP3; STAP2; NCSTN; CARD8
    protein kinase binding MAPK8IP2; PTPRC; KIF14; AKAP1; STAT3; RPS6KA3; PTPN2; CDC25C; RICTOR; SUFU
    vinculin binding SYNM; SORBS3; PXN; DAG1; C22orf28; DMD; CTNNA1; ACTN1; NRAP; TLN1
    zinc ion binding QPCT; OTUD7B; ADAMTS10; BMI1; MORC3; TLL2; MORC2B; ZDHHC5; NSD1; PHF23A

    PXN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PXN here. Most of them are supplied by our site. Hope this information will be useful for your research of PXN.

    PTK2; PTPN11; Sorbs1

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