protein l
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  • Official Full Name
  • Background
  • Protein L was first isolated from the surface of bacterial species Peptostreptococcus magnus and was found to bind immunoglobulins through L chain interaction, from which the name was suggested. It consists of 719 amino acid residues. The molecular weight of Protein L purified from the cell walls of Peptostreptoccus magnus was first estimated as 95kD by SDS-PAGE in the presence of reducing agent 2-mercaptoethanol, while the molecular weight was determined to 76kD by gel chromotography in the presence of 6 M guanidine HCl. Protein L does not contain any interchain disulfide loops, nor does it consist of disulfide-linked subunits. It was an acidic molecular with a PI of 4.0. Unlike Protein A and Protein G, which bind to the Fc region of immunoglobilins (antibodies), Protein L binds antibodies through light chain interactions. Since no part of the heavy chain is involved in the binding interaction, Protein L binds a wider range of antibody classes than Protein A or G. Protein L binds to representatives of all antibody classes, including IgG, IgM, IgA, IgE and IgD. Single chain variable fragments (scFv) and Fab fragments also bind to Protein L.
  • Synonyms
  • Protein L; PpL; Protein L Type 1 Protein; RPL; rProtein L
Cat.#:Protein L-528Tag:N/A
Source (Host):Species:Peptostreptoccocus magnus
Product nameRecombinant Staphylococcal L Protein, biotin-labeled
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Cat.#:Protein L-3141PTag:His
Source (Host):E. coliSpecies:Peptostreptococcus magnus
Product nameRecombinant Peptostreptococcus magnus Protein L protein, His-tagged
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Cat.#:Protein L-8141PTag:Biotin|His
Source (Host):E. coliSpecies:Peptostreptococcus magnus
Product nameRecombinant Peptostreptococcus magnus Protein L protein, Biotin/His-tagged
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Protein L Related Articles

Lin, JH; Wang, RH; et al. An impedance immunosensor based on low-cost microelectrodes and specific monoclonal antibodies for rapid detection of avian influenza virus H5N1 in chicken swabs. BIOSENSORS & BIOELECTRONICS 67:546-552(2015).
Mori, N; Ishikawa, C; et al. Activation of PKC-delta in HTLV-1-infected T cells. INTERNATIONAL JOURNAL OF ONCOLOGY 46:1609-1618(2015).