qrfpr
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  • Official Full Name
  • pyroglutamylated RFamide peptide receptor
  • Background
  • Pyroglutamylated RFamide peptide receptor also known as orexigenic neuropeptide QRFP receptor or G-protein coupled receptor 103 (GPR103) is a protein that in humans is encoded by the QRFPR gene.
  • Synonyms
  • QRFPR; pyroglutamylated RFamide peptide receptor; G protein coupled receptor 103 , GPR103; QRFP receptor; G protein-coupled receptor 103; G-protein coupled receptor 103; orexigenic neuropeptide QRFP receptor; AQ27; GPR103; SP9155; MGC149217
Cat.#:QRFPR-2093HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human QRFPR, His-tagged
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Cat.#:QRFPR-13766MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse QRFPR Protein
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Cat.#:QRFPR-4866RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat QRFPR Protein
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Cat.#:QRFPR-3837CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken QRFPR
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Involved Pathway

QRFPR involved in several pathways and played different roles in them. We selected most pathways QRFPR participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (q) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with QRFPR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)
EDN1; NTS; CXCR6; ADRA2B; NPB; SSTR5; DRD1; CCL27; S1PR5B; S1PR3
G alpha (q) signalling events
ABHD12; PROKR1A; PMCH; GPR68; DGKG; ADRA1D; TAC2; RGS19; TRIO; TRPC7
GPCR downstream signaling
GCGA; CNR2; OBSCN; PNOCB; PROK2; ABHD12; PTHLHA; CRHR1; ADCYAP1B; RHOC
GPCR ligand binding
OXGR1; GPR120; ADCYAP1; GAL; SETD6; SSTR4; GPR37L1; RAMP2; CXCR6; EMR4
Gastrin-CREB signalling pathway via PKC and MAPK
GPR132; RGS18; OPN4; KISS1; MGLL; CCK; TRH; EDN1; NMU; LPAR2A
Orexin and neuropeptides FF and QRFP bind to their respective receptors
NPFFR2; QRFP; HCRT; NPFF; QRFPR
Peptide ligand-binding receptors
TAC1; APLNR; GPR77; PENKB; FPR-RS6; NMS; PMCH; CCL27; CXCL11.8; MLN
Signal Transduction
ARHGAP25; ARHGAP44; CNR2; TMED5; KIF7; CSN2; EVC2; IRBP; TRIM33; RPE65B

Protein Function

QRFPR has several biochemical functions, for example, G-protein coupled receptor activity, neuropeptide Y receptor activity, peptide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by QRFPR itself. We selected most functions QRFPR had, and list some proteins which have the same functions with QRFPR. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein coupled receptor activity
Related Protein NPFFR1L3; SUCNR1; OLFR867; OLFR154; PTGDR2; TAS2R130; OR52J3; FFAR3; FPR-RS4; VMN1R52
Function neuropeptide Y receptor activity
Related Protein PROKR2; NPY5R; NPY8AR; PRLHR2B; PRLHR; NPY1R; PRLH2R; NPY8BR; NPY2R; PRLHR2A
Function peptide binding
Related Protein ANG; PLOD1; AVPR1B; OXTR; CMA1; NPFFR1L3; CRIP1; NUP98; CRHBP; OXTRL

QRFPR Related Articles

Primeaux, SD; et al. QRFP in female rats: Effects on high fat food intake and hypothalamic gene expression across the estrous cycle. PEPTIDES 32:1270-1275(2011).
Patel, SR; Murphy, KG; et al. Pyroglutamylated RFamide peptide 43 stimulates the hypothalamic-pituitary-gonadal axis via gonadotropin-releasing hormone in rats. ENDOCRINOLOGY 149:4747-4754(2008).
Fukusumi, S; Fujii, R; et al. Recent advances in mammalian RFamide peptides: The discovery and functional analyses of PrRP, RFRPs and QRFP. PEPTIDES 27:1073-1086(2006).
Fukusumi, S; Yoshida, H; et al. A new peptidic ligand and its receptor regulating adrenal function in rats. JOURNAL OF BIOLOGICAL CHEMISTRY 278:46387-46395(2003).