|Official Full Name||queuine tRNA-ribosyltransferase 1|
|Background||This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a;heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine;queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of;this gene is located on the long arm of chromosome X.|
|Synonyms||QTRT1; queuine tRNA-ribosyltransferase 1; queuine tRNA-ribosyltransferase; TGT; tRNA guanine transglycosylase; Guanine insertion enzyme; Queuine tRNA ribosyltransferase; TGUT; tRNA-guanine transglycosylase; FP3235|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
QTRT1 involved in several pathways and played different roles in them. We selected most pathways QTRT1 participated on our site, such as Gene Expression, tRNA modification in the nucleus and cytosol, tRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with QTRT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Gene Expression||ESR2B; ZNF224; ZNF234; MYBL1; SNAPC1A; RRN3; WDR77; DNMT1; NR1D2B; ZNF485|
|tRNA modification in the nucleus and cytosol||TRMT112; PUS1; OSGEP; METTL1; LBH; ALKBH8; TRMT11; ADAT1; TYW3; ADAT3|
|tRNA processing||THG1L; TRMT5; TP53RK; PUS7; POP4; TSEN2; TRMT11; CDKAL1; TRMT6; RPP38|
QTRT1 has several biochemical functions, for example, metal ion binding, contributes_to queuine tRNA-ribosyltransferase activity, queuine tRNA-ribosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by QTRT1 itself. We selected most functions QTRT1 had, and list some proteins which have the same functions with QTRT1. You can find most of the proteins on our site.
|metal ion binding||RARGA; CSNK2B; PLEKHF2; NDUFS7; NOTCH1A; NR1D2A; AOX3L1; SP5A; ZNF831; ZNF766|
|contributes_to queuine tRNA-ribosyltransferase activity||QTRT1; QTRTD1; MANEA|
|queuine tRNA-ribosyltransferase activity||QTRT1|
QTRT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with QTRT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of QTRT1.
ARF6; PA; ZBTB16; UNC119; SETDB1; COPS6; SH3GL3; NDUFA4L2