RAB13
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Official Full Name
RAB13, member RAS oncogene family
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Overview
Could participate in polarized transport, in the assembly and/or the activity of tight junctions. -
Synonyms
RAB13; RAB13, member RAS oncogene family; ras-related protein Rab-13; RAS-associated protein RAB13; growth-inhibiting gene 4 protein; cell growth-inhibiting gene 4 protein; GIG4;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- RAB13 Related Research Area
RAB13 involved in several pathways and played different roles in them. We selected most pathways RAB13 participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tight junction | ACTB1;MAGI1B;ACTN3A;INADL;MYH1B;CLDN2;CLDNB;JAM3B;CSNK2A2A |
RAB13 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB13 itself. We selected most functions RAB13 had, and list some proteins which have the same functions with RAB13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | ARL13B;RAP1AA;DAPK1;RAB14L;RHOU;RAN;RAP2A;GEM;RAB3DA |
| GTPase activity | TUBB6;RASD2;RRAGB;GNA14;IRGE4;MFN2;RAB39B;DNM2;REM2 |
| protein binding | BAG5;RAD1;CDK5R1;Shh;CDC25B;STK38L;IYD;BAD;TP73 |
RAB13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB13 here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB13.
Micall2; Leprotl1; PDE6D; gtp; PRKACA; OCRL; PRKACA
- Q&As
- Reviews
Q&As (6)
Ask a questionThe mutation types of RAB13 include point mutations, insertions, and deletions. Some of these mutations may cause dysfunction of RAB13, while others may affect its interaction with other proteins.
For people at high risk of RAB13 mutations, including those with cancer or other RAB13-related diseases, genetic testing can help doctors diagnose the condition more accurately and develop a corresponding treatment plan.
The impact of RAB13 mutations on disease progression can be assessed through in-depth analysis of the patient's genomic data. This can help doctors better understand the patient's condition and develop more effective treatment plans.
Its effect on disease can be predicted by comparing the structure and sequence of mutant and wild-type proteins. This can help doctors better understand the patient's condition and develop more effective treatment plans.
In clinical practice, treatment strategies for patients with RAB13 mutations need to consider the patient's specific condition, genotype, and treatment goals. Doctors can develop a personalized treatment plan based on the patient's actual situation to improve the treatment effect and maximize the patient's quality of life.
The expression level of RAB13 can be detected by immunohistochemistry, western blotting, real-time PCR, etc. These methods can detect protein or mRNA levels of RAB13 in tissues or cells to assess changes in its expression in disease.
Customer Reviews (3)
Write a reviewIt is very suitable for testing the rate of enzymatic reactions, and it performs very well.
RAB13 has a good labeling effect and can be used for fluorescent labeling, etc.
The clearance rate is high and the harm to the human body is small.
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