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RAB4A

  • Official Full Name

    RAB4A, member RAS oncogene family

  • Overview

    This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
  • Synonyms

    RAB4A; RAB4A, member RAS oncogene family; RAB4; HRES1; HRES-1; HRES-1/RAB4; ras-related protein Rab-4A; HTLV-1 related endogenous sequence;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RAB4A-710H Active Recombinant Human RAB4A Protein, GST/His-tagged E.coli GST/His
Human RAB4A-30976TH Recombinant Human RAB4A, T7 -tagged E.coli T7
Human RAB4A-31276TH Recombinant Human RAB4A E.coli N/A
Human RAB4A-3556H Recombinant Human RAB4A, His-tagged E.coli His
Human RAB4A-2129H Recombinant Human RAB4A, GST-tagged E.coli GST 0-218aa
Human RAB4A-2977H Recombinant Human RAB4A, T7-tagged E.coli T7
Human RAB4A-208H Recombinant Human RAB4A protein, T7-tagged E.coli T7
Human RAB4A-2589HCL Recombinant Human RAB4A 293 Cell Lysate HEK293 N/A
Human RAB4A-5609H Recombinant Human RAB4A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human RAB4A-3929H Recombinant Human RAB4A protein, His-tagged E.coli His 166-218 aa
Mouse Rab4a-5324M Recombinant Mouse Rab4a Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat RAB4A-4896R Recombinant Rat RAB4A Protein Mammalian Cell His
Rat RAB4A-4555R Recombinant Rat RAB4A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RAB4A-4555R-B Recombinant Rat RAB4A Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RAB4A-3755R Recombinant Rhesus monkey RAB4A Protein, His-tagged Mammalian Cell His
Rhesus Macaque RAB4A-3572R Recombinant Rhesus Macaque RAB4A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque RAB4A-3572R-B Recombinant Rhesus Macaque RAB4A Protein Pre-coupled Magnetic Beads HEK293
Zebrafish RAB4A-6708Z Recombinant Zebrafish RAB4A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RAB4A involved in several pathways and played different roles in them. We selected most pathways RAB4A participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EndocytosisWIPF2;PIP5K1AA;TGFB3;MHC1UEA;SMURF1;LDLRA;RUFY1;ZFYVE16;RAB7

RAB4A has several biochemical functions, for example, ATPase activator activity, ATPase binding, GDP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB4A itself. We selected most functions RAB4A had, and list some proteins which have the same functions with RAB4A. You can find most of the proteins on our site.

Function Related Protein
ATPase activator activityDNAJC10;TOR1AIP1;AHSA1;DNAJB1;DNAJB6;ATP1B2;AHSA1L;MYBPC3;TOR1AIP2
ATPase bindingDNAJC10;TOR1AIP1;ATP6V1G3;ABCA1;TAF9;GRIN2A;ATP6V0A1B;ATP6V0A4;PEX19
GDP bindingRALB;GEM;RRAGC;RRAS;RAP1B;RAB21;RAB8A;RAB5B;TRIM23
GTP bindingRAP1B;EEFSEC;GEM;HBS1L;HSP90AB1;ARL4AA;SEPT8B;IFT27;TUFM
GTPase activityRHOT2;ARL4C;RASD2;GNL2;RAB40B;RAB1B;RAB3DA;TUBA3D;EEF2B
ionotropic glutamate receptor bindingRAB4A;DLG4B;SHANK3;ADRB2;FLOT2;DLG2;NETO1;CANX;FUS
protein bindingPDGFC;C1orf50;RECK;RBM15;NLGN3;CABP5;TXNDC5;RPL36AL;CLN5
protein transporter activitySNUPN;RUFY1;KPNA1;COX18;CALCR;COG2;CCT6B;VPS26BL;AP1S3A
syntaxin bindingSNAP29;CPLX4A;PLDN;VPS54;ABCA1;DOC2B;CPLX4C;RPH3AL;SYTL3

RAB4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB4A here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB4A.

GDI1; gtp; EXOC5; VPS52; GDI2; PASK; APBB3; SOD2; TP53; IDH3A; PTTG1IP

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