rab4a
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  • Official Full Name
  • RAB4A, member RAS oncogene family
  • Background
  • This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
  • Synonyms
  • RAB4A; RAB4A, member RAS oncogene family; RAB4; HRES1; HRES-1; HRES-1/RAB4; ras-related protein Rab-4A; HTLV-1 related endogenous sequence;
Cat.#:RAB4A-3556HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB4A, His-tagged
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Cat.#:RAB4A-208HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB4A protein, T7-tagged
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Cat.#:RAB4A-2129HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB4A, GST-tagged
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Cat.#:RAB4A-2977HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB4A, T7-tagged
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Cat.#:RAB4A-30976THTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB4A, T7 -tagged
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Cat.#:RAB4A-31276THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB4A
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Cat.#:RAB4A-710HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB4A Protein, GST/His-tagged
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Cat.#:RAB4A-4896RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RAB4A Protein
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Cat.#:RAB4A-3755RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RAB4A Protein, His-tagged
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Cat.#:RAB4A-6708ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RAB4A
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Cat.#:RAB4A-2589HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RAB4A 293 Cell Lysate
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Involved Pathway

RAB4A involved in several pathways and played different roles in them. We selected most pathways RAB4A participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Endocytosis
CYTH3; IGF1R; RHOA; ARF6; DNM1A; NEDD4L; FAM125A; ARRB1; CYTH1A; ADRB3A

Protein Function

RAB4A has several biochemical functions, for example, ATPase activator activity, ATPase binding, GDP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB4A itself. We selected most functions RAB4A had, and list some proteins which have the same functions with RAB4A. You can find most of the proteins on our site.
Function
Related Protein
Function ATPase activator activity
Related Protein AHSA2; ATP1B1; DNAJC10; RAB4A; TOR1AIP1; DNAJC15; AHSA1; AHSA1L; DNAJB6; DNAJB1
Function ATPase binding
Related Protein NR1H2; LCK; UBXN1; ATPIF1B; SNX10; Ar; GRIN2A; ATP6V0A2B; ESR1; FXYD1
Function GDP binding
Related Protein RAB8A; PRPS2; RALB; RAP1B; SRP54B; RAB40C; RHOA; SEPT12; TRIM23; RAB9A
Function GTP binding
Related Protein RHOA; RHOJ; MXB; RND3; GTPBP1; RHOAD; RAB7L1; ARL5B; SEPT3; GMPPAA
Function GTPase activity
Related Protein RAN; EEF2B; TUBG1; GTPBP5; GNAI2; DNM3; HRAS; RAB36; RAB3B; RAB27B
Function ionotropic glutamate receptor binding
Related Protein IL1R1; RAB4A; DLG1L; ADRB2; NETO1; CACNG2; DLG1; GNAS; FUS; SHANK3
Function protein binding
Related Protein SLC38A2; BBS9; TRIP13; GPSM3; SERPINB8; CLK4; SAFB; MLC1; SENP1; PBXIP1
Function protein transporter activity
Related Protein TNPO3; COX18; FRAG1; VPS26BL; AP4S1; KPNA2; TSNAX; KPNA4; XPO6; AP2A1
Function syntaxin binding
Related Protein SYT17; SYT6; CAV1; CPLX3; BET1; RPH3AL; CPLX4B; SYT10; SYT15; SYTL4

Interacting Protein

RAB4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB4A here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB4A.
GDI1; gtp; EXOC5; VPS52; GDI2; PASK; APBB3; SOD2; TP53; IDH3A; PTTG1IP