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RAD54B

Official Full Name

RAD54 homolog B
Overview

The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
Synonyms

RAD54B; RAD54 homolog B (S. cerevisiae); DNA repair and recombination protein RAD54B; RDH54;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	RAD54B-1460HCL	Recombinant Human RAD54B cell lysate		N/A	Inquiry
Mouse	RAD54B-13876M	Recombinant Mouse RAD54B Protein	Mammalian Cell	His	Inquiry
Mouse	RAD54B-7391M	Recombinant Mouse RAD54B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	RAD54B-7391M-B	Recombinant Mouse RAD54B Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Chicken	RAD54B-6275C	Recombinant Chicken RAD54B	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

RAD54B involved in several pathways and played different roles in them. We selected most pathways RAD54B participated on our site, such as Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAD54B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Homologous recombination	TOP3A;XRCC3;SYCP3;XRCC2;RAD54L;RPA3;POLD2;RAD51D;CDK5R2

RAD54B has several biochemical functions, for example, ATP binding, DNA binding, DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAD54B itself. We selected most functions RAD54B had, and list some proteins which have the same functions with RAD54B. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	TARS;AURKA;CLK4;SUCLA2;ABCG2A;CHUK;HIPK1;DHX36;PDPK1A
DNA binding	DACH1;PPARGC1A;KDM1B;SP6;FOXJ1A;GM14479;HNRPDL;HLF;OLIG3
DNA helicase activity	MCM2;MCM5;ATRX;MCM6L;INO80;RUVBL1;IGHMBP2;CHD8;SUPV3L1
DNA translocase activity	FBXO18;ATRX;RAD54B
RNA helicase activity	CTU1;CHST13;UAP1L1;PRIM2;DHX15;CCDC111;DHX9;DDX6;DDX10

RAD54B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAD54B here. Most of them are supplied by our site. Hope this information will be useful for your research of RAD54B.

q8n374_human; TRAPPC6A; IGFBP3; PSMA1; CSNK1E; UBE2I; BAAT; CCDC33; LNX1; DYRK2; SFRP2; C9orf156; RIBC2; GORASP2; CDC23; ZNF580