rad54b
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  • Official Full Name
  • RAD54 homolog B
  • Background
  • The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
  • Synonyms
  • RAD54B; RAD54 homolog B (S. cerevisiae); DNA repair and recombination protein RAD54B; RDH54
Cat.#:RAD54B-13876MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RAD54B Protein
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Cat.#:RAD54B-6275CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RAD54B
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Cat.#:RAD54B-1460HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RAD54B cell lysate
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Involved Pathway

RAD54B involved in several pathways and played different roles in them. We selected most pathways RAD54B participated on our site, such as Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAD54B were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Homologous recombination
XRCC2; RAD51B; RPA2; EME1; RAD51C; POLD2; BRCA2; NBN; SSBP1; RPA3

Protein Function

RAD54B has several biochemical functions, for example, ATP binding, DNA binding, DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAD54B itself. We selected most functions RAD54B had, and list some proteins which have the same functions with RAD54B. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PRKAG3; OASL; STK40; TOP2A; SBK3; YES1; QRSL1; KIF1B; DYRK2; CCT2
Function DNA binding
Related Protein CMYB; ESRRGA; NR5A1; H2AFJ; ZBTB18; POLR2B; ESRRGB; C3orf37; DBX1A; MSXC
Function DNA helicase activity
Related Protein MCM5; RECQL5; RAD54B; MCM6L; PEO1; MCM2; CHD8; RECQL; RUVBL1; SUPV3L1
Function DNA translocase activity
Related Protein RAD54B; FBXO18; ATRX
Function RNA helicase activity
Related Protein UAP1L1; DHX16; DDX5; CTU1; DDX10; PRIM2; DHX15; DDX6; DDX17; DHX9

Interacting Protein

RAD54B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAD54B here. Most of them are supplied by our site. Hope this information will be useful for your research of RAD54B.
q8n374_human; TRAPPC6A; IGFBP3; PSMA1; CSNK1E; UBE2I; BAAT; CCDC33; LNX1; DYRK2; SFRP2; C9orf156; RIBC2; GORASP2; CDC23; ZNF580