• Official Full Name
  • Rho family GTPase 2
  • Background
  • This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1.
  • Synonyms
  • RND2; Rho family GTPase 2; ARHN, ras homolog gene family, member N; rho-related GTP-binding protein RhoN; Rho7; RhoN; ARHN; Rho 7; Rho N; Rho related GTP-binding protein RhoN; Rho-related GTP-binding protein Rho7; Rnd 2; RND2_HUMAN; GTP-binding protein Rho7; ras homolog gene family, member N
Source (Host):HEK293Species:Human
Product nameRecombinant Human RND2 Protein, MYC/DDK-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RND2, GST-tagged
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RND2 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RND2
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RND2
Source (Host):Species:Human
Product nameRecombinant Human RND2 293 Cell Lysate

Protein Function

RND2 has several biochemical functions, for example, GTP binding, GTPase activity, protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RND2 itself. We selected most functions RND2 had, and list some proteins which have the same functions with RND2. You can find most of the proteins on our site.
Related Protein
Function GTP binding
Related Protein TUBA1B; RND1; RAB25; MTIF2; GNAO1B; SAR1A; ERAL1; GMPPAA; RNF112; GNA11
Function GTPase activity
Related Protein RAB36; MX1; RNF112; GNAO1B; RAB5AB; RAB32; RAB4B; RAB7; DNAJC27; RAB32A
Function protein N-terminus binding
Related Protein GTF2H2; ERCC4; KCNQ2; TBL1XR1; STX5A; RND2; MYO7A; SNCA; MECP2; CSNK2A2
Function protein binding
Related Protein MIB1; ENOX1; ACTR3; LGALS13; PNMA5; FZD3; TOP3B; CRYBB1; EXOSC5; DOCK1

Interacting Protein

RND2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RND2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RND2.

RND2 Related Articles

Fichter, CD; Gudernatsch, V; et al. ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways. JOURNAL OF MOLECULAR MEDICINE-JMM 92:1209-1223(2014).
Sayyah, J; Bartakova, A; et al. The Ras-related Protein, Rap1A, Mediates Thrombin-stimulated, Integrin-dependent Glioblastoma Cell Proliferation and Tumor Growth. JOURNAL OF BIOLOGICAL CHEMISTRY 289:17689-17698(2014).