RNF133
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Official Full Name
ring finger protein 133
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Overview
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene has no intron. -
Synonyms
RNF133; ring finger protein 133; E3 ubiquitin-protein ligase RNF133; E3 ubiquitin protein ligase RNF133; MGC27072; RNF 133; OTTHUMP00000211453;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
RNF133 involved in several pathways and played different roles in them. We selected most pathways RNF133 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF133 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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RNF133 has several biochemical functions, for example, ligase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF133 itself. We selected most functions RNF133 had, and list some proteins which have the same functions with RNF133. You can find most of the proteins on our site.
Function | Related Protein |
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ligase activity | TRIM31;RTCB;TRIM23;RNF144AB;SYVN1;UBE2I;GLULC;CTPS1A;RNF212 |
zinc ion binding | CNBP;ADH8A;RNF113B;RAPSN;RABGEF1;ZDHHC3;C11orf54;FHL2;DPP3 |
RNF133 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF133 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF133.
UBE2H; UBE2I
- Q&As
- Reviews
Q&As (6)
Ask a questionThe interaction of RNF133 with other proteins or molecules is not fully understood. However, based on its structural and functional characteristics, it can be speculated that it may interact with some enzymes, transcription factors, or other signal transduction molecules to participate in the intracellular protein degradation process.
Mutations in RNF133 may have a variety of effects on cells, such as affecting intracellular protein degradation, leading to abnormal cell proliferation, and inducing apoptosis. These effects may be related to the occurrence of some diseases, such as neurological diseases, cancer, etc.
Molecular biology and biochemical methods, such as yeast two-hybridization, affinity chromatography, mass spectrometry, etc., can be used to study the interaction network of RNF133. These methods can help us understand the function and mechanism of action of RNF133 in cells.
RNF133 can be used as a biomarker for disease diagnosis and as a therapeutic target. For example, by detecting the expression levels or mutations of RNF133, doctors can be able to diagnose and evaluate the prognosis of certain diseases, and treatment strategies for RNF133 can also provide patients with more effective treatment options.
The expression level of RNF133 may be affected by a variety of factors, such as gene mutations, transcription factors, nutrients, etc. These factors may regulate the expression level of RNF133 by influencing its transcription and translation processes.
Cell models with overexpression or knockout of RNF133 can be established by gene transfection. The vector of the gene of interest or a specific knockout gene is introduced into the cells, and the stably expressed or knocked out cell line is obtained through screening and identification.
Customer Reviews (3)
Write a reviewEasy to purify and manipulate, easy to store, and easy to use.
The results are reliable and trustworthy.
RNF133 is easy to prepare, so we can easily prepare it ourselves.
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