rnf25
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  • Official Full Name
  • ring finger protein 25
  • Background
  • The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination.
  • Synonyms
  • RNF25; ring finger protein 25; E3 ubiquitin-protein ligase RNF25; AO7; FLJ13906; ring finger protein AO7
Cat.#:RNF25-671HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human RNF25 Protein, MYC/DDK-tagged
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Cat.#:RNF25-14341MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RNF25 Protein
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Cat.#:RNF25-2917CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RNF25
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Cat.#:RNF25-11400ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RNF25
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Cat.#:RNF25-1526HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RNF25 cell lysate
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Involved Pathway

RNF25 involved in several pathways and played different roles in them. We selected most pathways RNF25 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF25 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
LILRA3; RNF19B; RNF6; KLB; DCTN3; SLAMF6; DYNLL2; CTSL2; RNF41; CHUK
Antigen processing: Ubiquitination &
ASB4; LRRC41; HECTD3; ASB2; UBA5; FBXO44; ASB7; TRIM11; ATG7; ASB8
Proteasome degradation
TPP2; STUB1; ASB2; FBXO27; ASB10; TRIM11; VPRBP; LRSAM1; TRIM39; UBE2U
Class I MHC mediated antigen processing &
FBXO17; RNF123; FBXO27; HECTD3; GAN; FCGR1B; ERAP2; UBA5; ASB2; TPP2
presentation
GAN; LRRC41; CMTM2A; VPRBP; UBE2J2; UBE2L6; ASB17; TRAF7; DZIP3; LRSAM1
Immune System
POLR3G; TRIM56; RNF41; CLEC4A; MYO9B; MICA; KIF4; HUWE1; IFIT2; PANX1A
TNF-alpha/NF-kB Signaling Pathway
CAPN3; TNIP1; KTN1; PEG3; SMARCE1; NKIRAS2; LRPPRC; SMARCC2; DDX3X; PPP1R13L
Tryptophan metabolism
KYNU; ACAT2; AOX3; AADAT; CYP4F12; TPH1; CYP2F1; RNF25; ALDH9A1B; TPH1A

Protein Function

RNF25 has several biochemical functions, for example, NF-kappaB binding, ligase activity, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF25 itself. We selected most functions RNF25 had, and list some proteins which have the same functions with RNF25. You can find most of the proteins on our site.
Function
Related Protein
Function NF-kappaB binding
Related Protein BRMS1; CDKN2A; BCL10; HSPA6; HDAC1; RNF25; EP300; GSK3B; TAF4B; NFKBID
Function ligase activity
Related Protein NEDD4L; AMFR; RNF126; UBR1; SIAH2; CPS1; TRAF3; GLULC; TTLL2; UBE2D1A
Function ubiquitin protein ligase activity
Related Protein MED17; PARK2; RNF111; UBR1; CBLC; MED27; TRIP12; MSL2B; TRIM24; BTRC
Function ubiquitin-protein transferase activity
Related Protein UBE2H; TRIM56; UBE2O; G2E3; TRIM13; UBE2L3; RNF31; RNF168; FBXO4; RNF41
Function zinc ion binding
Related Protein CA4B; MT3; MPI; CUL9; ADAM9; VPS8; PCGF1; PGR; GATAD2B; MARCH1

Interacting Protein

RNF25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF25 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF25.
UBE2D1; UBE2E1; UBE2D3; UBE2D2; UBE2E3; UBE2D4; UBE2L6; TRIM27; UBE2U; UBE2E2