RNF43 Protein, ring finger protein 43


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Official Full Name ring finger protein 43
Synonyms RNF43;ring finger protein 43;18505;ENSG00000108375;URCC;RNF124;17q22;FLJ20315, FLJ77466, FLJ99338, MGC125630, DKFZp781H0392, DKFZp781H02126;E3 ubiquitin-protein ligase RNF43;E3 ubiquitin-protein ligase RNF43;
    • Species :
    • Human
    • Source :
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Tag :
    • Fc
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RNF43-1145H Recombinant Human RNF43 Mammalian Cell His
    Human RNF43-385H Recombinant Human RNF43, Fc-tagged Human Cell Fc
    Human RNF43-386H Recombinant Human RNF43, His-tagged Human Cell His
    Human RNF43-767H Recombinant Human RNF43 Protein, Fc-tagged HEK293 Fc
    Human RNF43-768H Recombinant Human RNF43 Protein, His-tagged HEK293 His

    RNF43 involved in several pathways and played different roles in them. We selected most pathways RNF43 participated on our site, such as Disease, Diseases of signal transduction, RNF mutants show enhanced WNT signaling and proliferation, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF43 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Disease MMAA; TICAM1; HEYL; NUPL2; IPO5; GYG2; AP2A2; HEY2; HDAC6; GPC5
    Diseases of signal transduction MYO18A; DERL2; CCNC; TNKS2; TRIM24; HEY2; OPN1LW; HEYL; RBP1; RBP4
    RNF mutants show enhanced WNT signaling and proliferation RNF43
    Regulation of FZD by ubiquitination LGR6; RSPO1; LGR4; RNF43; RSPO3; ZNRF3; LGR5; FMNL3; RSPO2; RSPO4
    Signal Transduction DLC1; FST; EMR4; CNR2; GPR132; MDKA; RNF31; FSTB; PDK3B; SOX13
    Signaling by WNT in cancer KREMEN1; TNKS2; RNF43; KREMEN2; TNKS
    Signaling by Wnt KREMEN1; SOX6; KREMEN2; DACT1; BCL9; FAM123B; CSNK1G2; LGR4; SOX4A; RBBP5
    TCF dependent signaling in response to WNT USP34; SOX9B; SOX4A; RSPO1; SOX7; CDC73; SOX4B; C; ASH2L; RNF146

    RNF43 has several biochemical functions, for example, frizzled binding, ligase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF43 itself. We selected most functions RNF43 had, and list some proteins which have the same functions with RNF43. You can find most of the proteins on our site.

    Function Related Protein
    frizzled binding WNT1; WNT4A; WNT4B; WNT7B; WNT8B; WNT2B; WNT16; WNT2BA; RNF43; BAMBI
    ligase activity MARCH9; RC3H2; NEDD4L; UBE2NB; SIAH2L; CDC34B; RNF182; TRIM56; TRIM68; UCHL1
    protein binding PDZD7; UBE2D3; AMPD2; SIK2; BIN3; PSME3; XRCC6; RBM41; C11orf57; GAPDHS
    ubiquitin-protein transferase activity RNF168; TRIM36; UBE2H; ZNRF1; UBE2C; FBXL14A; BIRC5B; UBE3A; HECTD1; FBXL3
    zinc ion binding PIAS1; KMT2E; TRIM65; ZMAT5; MMP10; SPRYD5; ZNRF4; TRIM35-22; ZNF92; RABGEF1L

    RNF43 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF43 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF43.


    Sakamoto, H; Kuboki, Y; et al. Clinicopathological significance of somatic RNF43 mutation and aberrant expression of ring finger protein 43 in intraductal papillary mucinous neoplasms of the pancreas. MODERN PATHOLOGY 28:261-267(2015).
    Xi, SY; Zhang, XK; et al. Downregulation of ring-finger protein 43 in glioma associates with poor prognosis. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 8:490-496(2015).

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