rpl28
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  • Official Full Name
  • ribosomal protein L28
  • Background
  • Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
  • Synonyms
  • RPL28; ribosomal protein L28; 60S ribosomal protein L28; FLJ43307; L28; FLJ 43307; L 28; RPL 28
Cat.#:RPL28-2390HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RPL28, GST-tagged
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Cat.#:RPL28-267HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RPL28 Protein, GST-His-tagged
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Cat.#:RPL28-14425MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RPL28 Protein
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Cat.#:RPL28-3984RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RPL28 Protein, His-tagged
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Cat.#:RPL28-11288ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RPL28
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Cat.#:RPL28-2209HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RPL28 293 Cell Lysate
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Involved Pathway

RPL28 involved in several pathways and played different roles in them. We selected most pathways RPL28 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL28 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ribosome
RPL23; RPL27; RPLP2; MRPL11; RPL5B; MRPL1; RPS7; MRPL19; MRPS14; MRPL34

Protein Function

RPL28 has several biochemical functions, for example, RNA binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL28 itself. We selected most functions RPL28 had, and list some proteins which have the same functions with RPL28. You can find most of the proteins on our site.
Function
Related Protein
Function RNA binding
Related Protein EIF4H; SMN2; NSUN5B; OASL2; SRSF3; CELF5; ELAVL1; DNMT1; DAZL; CSDC2
Function poly(A) RNA binding
Related Protein NPM1; BST2; ACAA2; FAM98A; CCDC137; HNRNPU; SUGP1; IPO5; SRP54; ATP5C1
Function protein binding
Related Protein BCL3; BCL7A; NAA30; CALCOCO1; ARMCX5; SYTL1; CCDC167; RGS14; FAM164C; PACSIN1
Function structural constituent of ribosome
Related Protein FAUB; MRPS31; MRPS14; MRPL34; MRPS6; RPL34; MRPL14; MRPL11; RPS24; MRPS18A

Interacting Protein

RPL28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL28 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL28.
CCNDBP1; DCC; 4505953; RTCA; MAGEB2; PSTPIP1; LYAR; UBE2D1; UBE2D3; MAP2K5; SMAD4; TMEM230; Srp72; Smad6; GABARAP